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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304676
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tollip
Name: toll interacting protein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tollipaffects expressionEXP 6480464CTDbisphenol A affects the expression of TOLLIP mRNAPMID:25181051
Tollipmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TOLLIP mRNAPMID:36041667
Tollipdecreases expressionISOTOLLIP (Homo sapiens)6480464CTDbisphenol A results in decreased expression of TOLLIP proteinPMID:31675489 PMID:34186270
Tollipincreases expressionISOTOLLIP (Homo sapiens)6480464CTDbisphenol A results in increased expression of TOLLIP mRNAPMID:29275510
Tollipmultiple interactionsISOTOLLIP (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of TOLLIP genePMID:31601247
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