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GENE - TERM ANNOTATION REPORT

RGD ID: 1303318
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tusc3
Name: tumor suppressor candidate 3
Acc ID: GO:0018279
Term: protein N-linked glycosylation via asparagine
Definition: The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.
Definition Source(s): GOC:jsg, RESID:AA0151, RESID:AA0420, RESID:AA0421
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tusc3involved_inISOTUSC3 (Canis lupus familiaris)1624291RGD PMID:12887896

PMID:12887896
Tusc3involved_inISOTUSC3 (Homo sapiens)1624291RGD PMID:26864433

PMID:26864433
Tusc3involved_inIEAUniProtKB:Q13454 or ensembl:ENSP000004245441600115EnsemblGO_REF:0000107

GO_REF:0000107
Tusc3involved_inIBAPANTHER:PTN000294174 or UniProtKB:Q13454 or UniProtKB:Q9H0U31600115GO_CentralGO_REF:0000033

GO_REF:0000033
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