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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303241
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bace2
Name: beta-secretase 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bace2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of BACE2 mRNAPMID:33387578
Bace2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of BACE2 mRNAPMID:34747641
Bace2affects expressionISOBace2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of BACE2 mRNAPMID:21570461
Bace2decreases expressionISOBACE2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of BACE2 mRNAPMID:23152189
Bace2increases expressionISOBace2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of BACE2 mRNAPMID:19770486
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