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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303035
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kif5a
Name: kinesin family member 5A
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kif5amultiple interactionsEXP 6480464CTD[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KIF5A protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of KIF5A mRNAPMID:37690569
Kif5adecreases expressionISOKIF5A (Homo sapiens)6480464CTDDiethylhexyl Phthalate results in decreased expression of KIF5A mRNAPMID:31163220
Kif5aincreases expressionISOKif5a (Mus musculus)6480464CTDDiethylhexyl Phthalate results in increased expression of KIF5A mRNAPMID:34319233
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