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GENE - TERM ANNOTATION REPORT

RGD ID: 12551382
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin beta 1
Acc ID: GO:0030877
Term: beta-catenin destruction complex
Definition: A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
Definition Source(s): PMID:14600025
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctnnb1part_ofIEAUniProtKB:P35222 or UniProtKB:Q02248 or ensembl:ENSMUSP00000007130 or ensembl:ENSP00000344456150520179Ensembl GO_REF:0000107
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