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GENE - TERM ANNOTATION REPORT

RGD ID: 12505597
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Tnfrsf1b
Name: TNF receptor superfamily member 1B
Acc ID: DOID:552
Term: pneumonia
Definition: A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Pneumonia "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf1b ISOTNFRSF1B (Homo sapiens)9068941RGDIdiopathic Pneumonia SyndromePMID:18664626 REF_RGD_ID:5131448
Tnfrsf1bsusceptibilityISOTNFRSF1B (Homo sapiens)9068941RGDassociated with Carcinoma, Non-Small-Cell Lung; DNA:snp:cds:p.M196R rs1061622 (human)PMID:20811626 REF_RGD_ID:5131286
Tnfrsf1b ISOTNFRSF1B (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:21625544
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