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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12429250
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: CYP1A1
Name: cytochrome P450 family 1 subfamily A member 1
Acc ID: CHEBI:28909
Term: iprodione
Definition: An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide.
Chemical ID: MESH:C033148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1A1multiple interactionsEXP 6480464CTD[iprodione binds to and results in increased activity of AHR protein] which results in increased activity of CYP1A1 proteinPMID:24389113
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