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GENE - TERM ANNOTATION REPORT

RGD ID: 12386781
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: PSAP
Name: prosaposin
Acc ID: GO:0005764
Term: lysosome
Definition: A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
Definition Source(s): GOC:mah, ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PSAPlocated_inIEAUniProtKB:P07602 or ensembl:ENSP00000378394150520179Ensembl GO_REF:0000107
PSAPis_active_inIBAMGI:97783 or PANTHER:PTN000159370 or UniProtKB:P07602150520179GO_Central GO_REF:0000033
PSAPlocated_inIEAInterPro:IPR008373 or InterPro:IPR021165150520179InterPro GO_REF:0000002
PSAPlocated_inIEAUniRule:UR000342797150520179UniProt GO_REF:0000104
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