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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12063362
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
Acc ID: CHEBI:6532
Term: loperamide
Definition: A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Chemical ID: MESH:D008139
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCB1affects response to substanceEXP 6480464CTDABCB1 protein affects the susceptibility to LoperamidePMID:25660379
ABCB1increases exportEXP 6480464CTDABCB1 protein results in increased export of LoperamidePMID:28093773
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