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GENE - TERM ANNOTATION REPORT

RGD ID: 12052181
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: F7
Name: coagulation factor VII
Acc ID: DOID:9007692
Term: Insulin Resistance
Definition: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Definition Source(s): MESH:D007333
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F7severityISOF7 (Homo sapiens)9068941RGDassociated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human)PMID:9187410 REF_RGD_ID:2312406
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