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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11481
Species: Mus musculus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1affects expressionEXP 6480464CTDAcetaminophen affects the expression of VCAM1 mRNAPMID:17562736
Vcam1increases expressionEXP 6480464CTDAcetaminophen results in increased expression of VCAM1 mRNAPMID:11264010 PMID:12051698 PMID:12153990 PMID:12540782 PMID:14557383 PMID:18544908
Vcam1multiple interactionsEXP 6480464CTDIFNG protein promotes the reaction [Acetaminophen results in increased expression of VCAM1 mRNA]; O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of VCAM1 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of VCAM1 mRNA]PMID:12153990 PMID:12540782 PMID:14557383
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