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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11354
Species: Mus musculus
RGD Object: Gene
Symbol: Sult2a1
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Acc ID: CHEBI:16359
Term: cholic acid
Definition: A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Chemical ID: MESH:D019826
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sult2a1increases expressionEXP 6480464CTDCholic Acid results in increased expression of SULT2A1 mRNAPMID:17521389 PMID:22961653
Sult2a1increases sulfationISOSULT2A1 (Homo sapiens)6480464CTDSULT2A1 protein results in increased sulfation of Cholic AcidPMID:20102295
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