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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11160
Species: Mus musculus
RGD Object: Gene
Symbol: Prnp
Name: prion protein
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prnpaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PRNP mRNAPMID:21570461
Prnpmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRNP mRNAPMID:17942748
Prnpaffects expressionISOPrnp (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of PRNP mRNAPMID:34747641
Prnpdecreases expressionISOPrnp (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PRNP mRNAPMID:33387578
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