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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10922
Species: Mus musculus
RGD Object: Gene
Symbol: Mt1
Name: metallothionein 1
Acc ID: CHEBI:18248
Term: iron atom
Definition: An iron group element atom that has atomic number 26.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt1increases expressionEXP 6480464CTDIron deficiency results in increased expression of MT1 mRNAPMID:23776592 PMID:24089420
Mt1multiple interactionsEXP 6480464CTDATP7A gene mutant form promotes the reaction [Iron deficiency results in increased expression of MT1 mRNA]PMID:23776592
Mt1increases expressionISOMt1 (Rattus norvegicus)6480464CTDIron deficiency results in increased expression of MT1A; Iron deficiency results in increased expression of MT1A mRNAPMID:16629162 PMID:21852364
Mt1multiple interactionsISOMt1 (Rattus norvegicus)6480464CTD[Zinc co-treated with Iron] results in increased expression of and affects the localization of MT1A protein; Iron results in increased expression of and affects the localization of MT1A proteinPMID:17241390
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