GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsd11b2 | increases expression | ISO | HSD11B2 (Homo sapiens) | 6480464 | CTD | Bexarotene results in increased expression of HSD11B2 mRNA | PMID:31927052 | Hsd11b2 | multiple interactions | ISO | HSD11B2 (Homo sapiens) | 6480464 | CTD | Bexarotene results in increased expression of and results in increased activity of HSD11B2 protein; Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; LG 100754 inhibits the reaction [Bexarotene results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [Bexarotene results in increased expression of HSD11B2 protein] | PMID:31927052 | | ||||||||||||||||||||||
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