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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10246
Species: Mus musculus
RGD Object: Gene
Symbol: Brca1
Name: breast cancer 1, early onset
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brca1decreases expressionISOBRCA1 (Homo sapiens)6480464CTDCadmium results in decreased expression of BRCA1 mRNA; Cadmium results in decreased expression of BRCA1 proteinPMID:20049202 PMID:31646340
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