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GENE - TERM ANNOTATION REPORT

3 Annotations Found.

An association has been curated linking Six1 and nephroblastoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Wegert J, etal., Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002.
  • The annotation has been inferred from sequence orthology with SIX1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Wegert J, etal., Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002.
  • 149 RGD objects have been annotated to nephroblastoma  (DOID:2154)
  • 28 papers in RGD have been used to annotate Six1
  • Qualifier: severity
  • Curation Notes: DNA:missense mutation:cds:p.Q177R (human)


    • An association has been curated linking Six1 and nephroblastoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Sehic D, etal., Pediatr Blood Cancer. 2012 Jul 15;59(1):62-8. doi: 10.1002/pbc.24025. Epub 2011 Dec 16.
  • The annotation has been inferred from sequence orthology with SIX1 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Sehic D, etal., Pediatr Blood Cancer. 2012 Jul 15;59(1):62-8. doi: 10.1002/pbc.24025. Epub 2011 Dec 16.
  • 149 RGD objects have been annotated to nephroblastoma  (DOID:2154)
  • 28 papers in RGD have been used to annotate Six1
  • Qualifier: severity
  • Curation Notes: protein:increased expression:kidney, blastema (human)


    • An association has been curated linking Six1 and nephroblastoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with SIX1 (Homo sapiens) [(EXP) inferred from experiment]
  • 149 RGD objects have been annotated to nephroblastoma  (DOID:2154)
  • 28 papers in RGD have been used to annotate Six1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:28825729


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