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GENE - TERM ANNOTATION REPORT

13 Annotations Found.

An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Charison J, etal., Can J Diabetes. 2016 Jun;40(3):210-5. doi: 10.1016/j.jcjd.2015.10.003. Epub 2016 Mar 3.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 4 additional annotations were made from Charison J, etal., Can J Diabetes. 2016 Jun;40(3):210-5. doi: 10.1016/j.jcjd.2015.10.003. Epub 2016 Mar 3.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Qualifier: onset
  • Curation Notes: DNA:SNP:cds: p.G319S (human)


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ley SH, etal., Cardiovasc Diabetol. 2010 Aug 18;9:39. doi: 10.1186/1475-2840-9-39.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Ley SH, etal., Cardiovasc Diabetol. 2010 Aug 18;9:39. doi: 10.1186/1475-2840-9-39.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Qualifier: susceptibility
  • Curation Notes: DNA:SNP:cds: p.G319S (human)


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ellard S, etal., Diabetologia. 2007 Nov;50(11):2313-7. Epub 2007 Sep 8.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Ellard S, etal., Diabetologia. 2007 Nov;50(11):2313-7. Epub 2007 Sep 8.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Curation Notes: DNA:deletions:exon:multiple


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Holmkvist J, etal., Diabetes. 2008 Jun;57(6):1738-44. Epub 2008 Mar 10.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 6 additional annotations were made from Holmkvist J, etal., Diabetes. 2008 Jun;57(6):1738-44. Epub 2008 Mar 10.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Qualifier: susceptibility
  • Curation Notes: DNA:SNP::rs1169288 associated with future risk of developing T2DM (p=0.0002) (human)


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Yamagata K, etal., Nature. 1996 Dec 5;384(6608):455-8.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Yamagata K, etal., Nature. 1996 Dec 5;384(6608):455-8.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Qualifier: susceptibility
  • Curation Notes: Maturity-onset diabetes of the young type III, OMIM:600496;DNA:insertions, deletions, point mutations: :multiple


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Bellanne-Chantelot C, etal., Diabetes. 2008 Feb;57(2):503-8. Epub 2007 Nov 14.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Bellanne-Chantelot C, etal., Diabetes. 2008 Feb;57(2):503-8. Epub 2007 Nov 14.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Qualifier: onset
  • Curation Notes: DNA:nonsense mutations, missense mutations: :multiple


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from OMIM Disease Annotation Pipeline
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(EXP) inferred from experiment]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:28869590


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ley SH, etal., BMC Med Genet. 2011 Jan 5;12:1. doi: 10.1186/1471-2350-12-1.
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Ley SH, etal., BMC Med Genet. 2011 Jan 5;12:1. doi: 10.1186/1471-2350-12-1.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Qualifier: susceptibility
  • Curation Notes: associated with nicotine dependence; DNA:SNP:cds: p.G319S (human)


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Curation Notes: ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to | ClinVar Annotator: match by term: Insulin-resistant diabetes mellitus | ClinVar Annotator: match by term: Type 2 diabetes mellitus
  • Original References(s): PMID:10084598 PMID:10333057 PMID:10588527 PMID:10634407 PMID:10843190 PMID:10852449 PMID:11058894 PMID:11904371 PMID:11942313 PMID:12355088 PMID:12359128 PMID:12574234 PMID:12627330 PMID:12675668 PMID:12788852 PMID:12832318 PMID:15031772 PMID:15657605 PMID:15761192 PMID:15883474 PMID:15928245 PMID:16917892 PMID:16963153 PMID:17033837 PMID:17062882 PMID:17192490 PMID:17220065 PMID:17407072 PMID:17425917 PMID:17440016 PMID:17573900 PMID:17937063 PMID:18003757 PMID:18332101 PMID:18414213 PMID:18439552 PMID:18498634 PMID:18811724 PMID:19672314 PMID:19754856 PMID:20031592 PMID:20393147 PMID:20690076 PMID:20705777 PMID:21170474 PMID:21761282 PMID:23139355 PMID:23274891 PMID:23348805 PMID:23607861 PMID:24033266 PMID:24097065 PMID:24728327 PMID:24915262 PMID:24933231 PMID:25057215 PMID:25555642 PMID:25741868 PMID:26059258 PMID:26431509 PMID:26467025 PMID:26981542 PMID:27035118 PMID:27458973 PMID:27899486 PMID:28105082 PMID:28492532 PMID:29207974 PMID:29376044 PMID:29758564 PMID:29844095 PMID:30155490 PMID:30202817 PMID:31109344 PMID:31264968 PMID:31385057 PMID:31485449 PMID:31566143 PMID:31673528 PMID:31844173 PMID:31968565 PMID:32910913 PMID:32928877 PMID:33477506 PMID:33651556 PMID:34668636 PMID:34803393 PMID:35218126 PMID:35328643 PMID:8945470 PMID:9112026 PMID:9133564 PMID:9287053 PMID:9313764 PMID:9604876 PMID:9867222


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
    		•  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Hnf1a (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Curation Notes: OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Curation Notes: ClinVar Annotator: match by term: DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST | ClinVar Annotator: match by term: Insulin-resistant diabetes mellitus | ClinVar Annotator: match by term: Type 2 diabetes mellitus | ClinVar Annotator: match by term: Type II diabetes mellitus
  • Original References(s): PMID:10084598 PMID:10333057 PMID:10588527 PMID:10634407 PMID:10843190 PMID:10852449 PMID:11058894 PMID:11904371 PMID:11942313 PMID:12355088 PMID:12359128 PMID:12574234 PMID:12627330 PMID:12675668 PMID:12788852 PMID:12832318 PMID:15031772 PMID:15657605 PMID:15761192 PMID:15883474 PMID:15928245 PMID:16186275 PMID:16241915 PMID:16917892 PMID:16963153 PMID:17033837 PMID:17062882 PMID:17116178 PMID:17192490 PMID:17220065 PMID:17407072 PMID:17425917 PMID:17440016 PMID:17573900 PMID:17937063 PMID:18003757 PMID:18332101 PMID:18414213 PMID:18439552 PMID:18498634 PMID:18586913 PMID:18811724 PMID:19672314 PMID:19754856 PMID:20031592 PMID:20393147 PMID:20690076 PMID:20705777 PMID:21170474 PMID:21761282 PMID:23139355 PMID:23348805 PMID:23607861 PMID:24097065 PMID:24728327 PMID:24915262 PMID:24933231 PMID:25057215 PMID:25555642 PMID:25741868 PMID:26059258 PMID:26431509 PMID:26467025 PMID:26981542 PMID:27035118 PMID:27130141 PMID:27458973 PMID:27899486 PMID:28105082 PMID:28492532 PMID:29207974 PMID:29376044 PMID:29758564 PMID:29844095 PMID:29895593 PMID:30155490 PMID:30202817 PMID:31109344 PMID:31264968 PMID:31385057 PMID:31485449 PMID:31517624 PMID:31566143 PMID:31673528 PMID:31844173 PMID:31968565 PMID:32041611 PMID:32395877 PMID:32910913 PMID:32928877 PMID:33363396 PMID:33477506 PMID:33651556 PMID:34668636 PMID:34803393 PMID:35299962 PMID:35328643 PMID:35673428 PMID:8945470 PMID:9112026 PMID:9133564 PMID:9287053 PMID:9313764 PMID:9604876


    • An association has been curated linking Hnf1a and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with HNF1A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 52 papers in RGD have been used to annotate Hnf1a
  • Curation Notes: ClinVar Annotator: match by term: DIABETES MELLITUS, TYPE 2, PROTECTION AGAINST | ClinVar Annotator: match by term: Diabetes mellitus type 2, susceptibility to | ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset | ClinVar Annotator: match by term: Insulin-resistant diabetes mellitus | ClinVar Annotator: match by term: Type 2 diabetes mellitus | ClinVar Annotator: match by term: Type II diabetes mellitus
  • Original References(s): PMID:10084598 PMID:10333057 PMID:10588527 PMID:10634407 PMID:10843190 PMID:10852449 PMID:10966642 PMID:11058894 PMID:11296231 PMID:11393552 PMID:11904371 PMID:11942313 PMID:12355088 PMID:12359128 PMID:12574234 PMID:12627330 PMID:12675668 PMID:12788852 PMID:12832318 PMID:15031772 PMID:15649945 PMID:15657605 PMID:15761192 PMID:15883474 PMID:15928245 PMID:16186275 PMID:16241915 PMID:16917892 PMID:16963153 PMID:17033837 PMID:17062882 PMID:17116178 PMID:17192490 PMID:17220065 PMID:17407072 PMID:17425917 PMID:17440016 PMID:17573900 PMID:17937063 PMID:18003757 PMID:18332101 PMID:18414213 PMID:18439552 PMID:18498634 PMID:18586913 PMID:18811724 PMID:19169489 PMID:19672314 PMID:19754856 PMID:19929997 PMID:20031592 PMID:20393147 PMID:20690076 PMID:20705777 PMID:21170474 PMID:21696527 PMID:21761282 PMID:22348187 PMID:22432108 PMID:23139355 PMID:23348805 PMID:23607861 PMID:24097065 PMID:24728327 PMID:24915262 PMID:24933231 PMID:25057215 PMID:25555642 PMID:25741868 PMID:26059258 PMID:26431509 PMID:26467025 PMID:26981542 PMID:27035118 PMID:27130141 PMID:27148439 PMID:27458973 PMID:27899486 PMID:28105082 PMID:28395978 PMID:28492532 PMID:29207974 PMID:29376044 PMID:29758564 PMID:29844095 PMID:29895593 PMID:30155490 PMID:30202817 PMID:30293189 PMID:30455330 PMID:31109344 PMID:31264968 PMID:31365591 PMID:31385057 PMID:31485449 PMID:31517624 PMID:31566143 PMID:31576961 PMID:31638168 PMID:31673528 PMID:31844173 PMID:31968565 PMID:32041611 PMID:32238361 PMID:32395877 PMID:32910913 PMID:32928877 PMID:33363396 PMID:33477506 PMID:33651556 PMID:34668636 PMID:34803393 PMID:35299962 PMID:35328643 PMID:35673428 PMID:8945470 PMID:9075818 PMID:9112026 PMID:9133564 PMID:9287053 PMID:9313764 PMID:9392505 PMID:9604876 PMID:9754819


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