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GENE - TERM ANNOTATION REPORT

6 Annotations Found.

An association has been curated linking GRN and Alzheimer's disease in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Pereson S, etal., J Pathol. 2009 Oct;219(2):173-81.
  • The annotation has been inferred from sequence orthology with Grn (Mus musculus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Pereson S, etal., J Pathol. 2009 Oct;219(2):173-81.
  • 755 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 35 papers in RGD have been used to annotate GRN
  • Qualifier: severity
  • Curation Notes: mRNA, protein:increased expression:microglia, neuron:


    • An association has been curated linking GRN and Alzheimer's disease in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Brouwers N, etal., Neurology. 2008 Aug 26;71(9):656-64. Epub 2008 Jun 18.
  • 2 additional annotations were made from Brouwers N, etal., Neurology. 2008 Aug 26;71(9):656-64. Epub 2008 Jun 18.
  • 755 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 35 papers in RGD have been used to annotate GRN
  • Curation Notes: DNA:mutations: :


    • An association has been curated linking GRN and Alzheimer's disease in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Viswanathan J, etal., Am J Med Genet B Neuropsychiatr Genet. 2009 Jul 5;150B(5):747-50. doi: 10.1002/ajmg.b.30889.
  • 3 additional annotations were made from Viswanathan J, etal., Am J Med Genet B Neuropsychiatr Genet. 2009 Jul 5;150B(5):747-50. doi: 10.1002/ajmg.b.30889.
  • 755 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 35 papers in RGD have been used to annotate GRN
  • Curation Notes: DNA:SNPs: :rs5848, rs850713, rs4792939 (human)


    • An association has been curated linking GRN and Alzheimer's disease in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Dickson DW, etal., Neurodegener Dis. 2010;7(1-3):170-4. Epub 2010 Mar 3.
  • 2 additional annotations were made from Dickson DW, etal., Neurodegener Dis. 2010;7(1-3):170-4. Epub 2010 Mar 3.
  • 755 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 35 papers in RGD have been used to annotate GRN
  • Curation Notes: DNA:SNP:3'UTR:rs5848(human)


    • An association has been curated linking GRN and Alzheimer's disease in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Kelley BJ, etal., Arch Neurol. 2010 Feb;67(2):171-7.
  • 2 additional annotations were made from Kelley BJ, etal., Arch Neurol. 2010 Feb;67(2):171-7.
  • 755 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 35 papers in RGD have been used to annotate GRN
  • Qualifier: onset
  • Curation Notes: DNA:deletion:exon:c.154delA(human)


    • An association has been curated linking GRN and Alzheimer's disease in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred by association of genotype and phenotype with RGD:14349951 (Homo sapiens)
  • 755 RGD objects have been annotated to Alzheimer's disease  (DOID:10652)
  • 35 papers in RGD have been used to annotate GRN
  • Curation Notes: ClinVar Annotator: match by term: Alzheimer disease
  • Original References(s): PMID:16199547 PMID:16862116 PMID:16950801 PMID:22608501 PMID:28492532 PMID:30279455 PMID:31031559


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