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| Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Site |
Method Duration |
Post Insult Time Value |
Record ID |
Study ID |
| MWF/FubRkb |
mesenteric artery wall thickness |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
mesenteric artery morphology trait |
male |
114.0 days
| 10 |
37.7 |
um |
1.9 |
6.01 |
confocal microscopy |
|
0.0 |
|
109422 |
3140 |
| MWF/FubRkb |
systolic blood pressure |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
arterial blood pressure trait |
male |
112.0 days
| 10 |
133.9 |
mmHg |
9.0 |
28.46 |
tail cuff plethysmography |
|
0.0 |
|
109410 |
3140 |
| MWF/FubRkb |
pulse wave velocity |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
arterial blood pressure trait |
male |
112.0 days
| 10 |
5.6 |
/ms |
0.5 |
1.58 |
tail cuff plethysmography |
|
0.0 |
|
109418 |
3140 |
| MWF/FubRkb |
mesenteric artery adventitial thickness |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
mesenteric artery morphology trait |
male |
114.0 days
| 10 |
7.9 |
um |
0.5 |
1.58 |
confocal microscopy |
|
0.0 |
|
109426 |
3140 |
| MWF/FubRkb |
norepinephrine-induced blood vessel contractile force expressed as percent of force of contraction to KCL |
finerenone (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
vasoconstriction trait |
male |
114.0 days
| 10 |
52.9 |
% |
7.9 |
24.98 |
wire myography |
|
0.0 |
|
109442 |
3140 |
| MWF/FubRkb |
negative logarithm of the molar concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value |
finerenone (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
vasoconstriction trait |
male |
114.0 days
| 10 |
6.7 |
null |
0.1 |
0.32 |
wire myography |
|
0.0 |
|
109446 |
3140 |
| MWF/FubRkb |
mesenteric artery media thickness |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
mesenteric artery morphology trait |
male |
114.0 days
| 10 |
19.3 |
um |
0.9 |
2.85 |
confocal microscopy |
|
0.0 |
|
109430 |
3140 |
| MWF/FubRkb |
body weight |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
body mass |
male |
112.0 days
| 10 |
350.3 |
g |
9.0 |
28.46 |
body weighing method |
|
0.0 |
|
109390 |
3140 |
| MWF/FubRkb |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
vasodilation trait |
male |
114.0 days
| 10 |
89.6 |
% |
1.6 |
5.06 |
wire myography |
mesenteric artery |
0.0 |
|
109434 |
3140 |
| MWF/FubRkb |
heart rate |
finerenone (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
heart pumping trait |
male |
112.0 days
| 10 |
353.7 |
beats/min |
6.1 |
19.29 |
tail cuff plethysmography |
heart |
0.0 |
|
109414 |
3140 |
|