| SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 5 |
|
1.49 |
g |
0.1 |
0.23 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
remnant kidney |
101546 |
2602 |
| SD |
systolic blood pressure |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
days
| 6 |
undefined |
186.0 |
mmHg |
10.61 |
26.0 |
tail cuff plethysmography |
0.0 |
unx |
28 |
days |
|
101586 |
2602 |
| SD |
change in body weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
days
| 5 |
|
66.0 |
g |
4.92 |
11.0 |
body weighing method |
0.0 |
unx |
13 |
days |
change from surgery weight |
101542 |
2602 |
| SD |
plasma renin activity level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
renin activity |
male |
days
| 5 |
|
5.2 |
ng/ml/h |
2.24 |
5.0 |
radioimmunoassay |
0.0 |
unx |
13 |
days |
|
101566 |
2602 |
| SD |
plasma potassium level |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood potassium amount |
male |
days
| 6 |
|
4.5 |
mmol/l |
0.2 |
0.5 |
ex vivo blood analysis |
0.0 |
unx |
28 |
days |
|
101598 |
2602 |
| SD |
body weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
days
| 5 |
|
302.0 |
g |
6.26 |
14.0 |
body weighing method |
0.0 |
unx |
13 |
days |
|
101538 |
2602 |
| SD |
urine total protein excretion rate |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
days
| 6 |
|
217.0 |
mg/d |
28.99 |
71.0 |
urine protein analysis |
0.0 |
unx |
28 |
days |
|
101594 |
2602 |
| SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
days
| 6 |
|
25.3 |
% |
4.53 |
11.1 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
101606 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 5 |
|
60.0 |
mg |
3.13 |
7.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
101562 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 6 |
|
60.0 |
mg |
3.27 |
8.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101602 |
2602 |
| SD |
systolic blood pressure |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
arterial blood pressure trait |
male |
days
| 5 |
undefined |
149.0 |
mmHg |
9.39 |
21.0 |
tail cuff plethysmography |
0.0 |
unx |
13 |
days |
|
101550 |
2602 |
| SD |
urine total protein excretion rate |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
total urine protein amount |
male |
days
| 5 |
|
87.0 |
mg/d |
12.52 |
28.0 |
urine protein analysis |
0.0 |
unx |
13 |
days |
|
101554 |
2602 |
| SD |
plasma aldosterone level |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
blood aldosterone amount |
male |
days
| 5 |
|
487.0 |
pg/ml |
50.98 |
114.0 |
plasma aldosterone analysis |
0.0 |
unx |
13 |
days |
|
101558 |
2602 |
| SD |
body weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
days
| 6 |
|
312.0 |
g |
9.8 |
24.0 |
body weighing method |
0.0 |
unx |
28 |
days |
|
101574 |
2602 |
| SD |
change in body weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
body mass |
male |
days
| 6 |
|
106.0 |
g |
10.61 |
26.0 |
body weighing method |
0.0 |
unx |
28 |
days |
change from surgery weight |
101578 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 6 |
|
2.03 |
g |
0.2 |
0.48 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
remnant kidney |
101582 |
2602 |
| SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 6 |
|
1.28 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101590 |
2602 |