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| Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Type |
Post Insult Time Value |
Post Insult Time Unit |
Record ID |
Study ID |
| BN |
liver tumorous lesion number |
N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy |
Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. |
liver integrity trait |
female |
days
| 3 |
1717.0 |
null |
227.0 |
393.18 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethtlamine injection |
56 |
days |
68618 |
950 |
| BN |
ratio of apoptotic bodies to intact tumor cells in remodelling liver tumorous lesions |
N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and controlled 2-acetamidofluorene content diet (0.02 %) then partial hepatectomy |
De Miglio MR, et al., Int J Cancer 2003 May 20;105(1):70-5. |
liver integrity trait |
not specified |
days
| |
2.08 |
% |
|
0.18 |
ex vivo light microscopy with immunohistochemistry and digital image analysis |
0.0 |
|
|
|
84783 |
1603 |
| BN |
volume of liver occupied by tumorous lesions as percentage of total liver volume |
N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy |
Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. |
liver integrity trait |
female |
days
| 3 |
1.61 |
% |
0.46 |
0.8 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethtlamine injection |
56 |
days |
68620 |
950 |
| BN |
ratio of apoptotic bodies to intact tumor cells in nonremodelling liver tumorous lesions |
N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and controlled 2-acetamidofluorene content diet (0.02 %) then partial hepatectomy |
De Miglio MR, et al., Int J Cancer 2003 May 20;105(1):70-5. |
liver integrity trait |
not specified |
days
| |
1.55 |
% |
|
0.09 |
ex vivo light microscopy with immunohistochemistry and digital image analysis |
0.0 |
|
|
|
84780 |
1603 |
| BN |
liver remodeling tumorous lesion number to liver total tumorous lesion number ratio |
N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy then 5-bromo-2'-deoxyuridine (50 mg/kg) (for 2 hours) |
Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. |
liver integrity trait |
male |
days
| 5 |
180.0 |
% |
4.0 |
8.94 |
ex vivo light microscopy with digital image analysis |
0.0 |
N-nitrosodiethtlamine injection |
56 |
days |
69144 |
950 |
|