DA/Bkl |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (0.1 ml) |
Cannon GW, et al., J Rheumatol 1993 Jan;20(1):7-11 |
joint integrity trait |
male |
70 days-105 days |
10 |
14.4 |
d |
1.3 |
4.11 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69554 |
1158 |
DA/Bkl |
calculated serum anti-porcine type 2 collagen antibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood immunoglobulin amount |
both |
66 days-126 days |
105 |
19.0 |
null |
0.59 |
6.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69962 |
850 |
BN/SsN |
calculated serum anti-porcine type 2 collagen antibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood immunoglobulin amount |
both |
66 days-126 days |
13 |
3.0 |
null |
0.55 |
2.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69964 |
850 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65 days-112 days |
21 |
11.7 |
d |
2.23 |
10.2 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69490 |
837 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
13 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69715 |
1162 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69723 |
1162 |
DA/Ztm |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
12 |
790.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69756 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
14 |
500.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69758 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
14 |
12.5 |
% |
0.9 |
3.37 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69800 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
male |
120 days-200 days |
13 |
6.6 |
% |
1.3 |
4.69 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69803 |
1162 |
DA/Ztm |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
12 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69709 |
1162 |
PVG.1AV1 |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
15 |
33.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69710 |
1162 |
DA.PVG.1AV1-(D4Rat113-D4Kiru96)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 8 |
14.4 |
d |
1.73 |
4.9 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84923 |
1301 |
DA.PVG.1AV1-(D4Got126-D4Got136) |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 14 |
19.0 |
d |
1.18 |
4.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84924 |
1301 |
DA.LEW.1AV1-(D4Mgh17-D4Mgh21)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 14 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84873 |
1301 |
DA.PVG.1AV1-(D4Rat231-D4Mit12)/Kini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84883 |
1301 |
DA/ZtmKini |
thymus weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
thymus mass |
male |
0 days
| 8 |
0.6 |
mg/g |
0.07 |
0.19 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
84932 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
0 |
15.6 |
d |
|
9.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69499 |
837 |
DA/ZtmKini |
inguinal lymph node wet weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
inguinal lymph node mass |
male |
0 days
| 8 |
0.68 |
g/kg |
0.07 |
0.21 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
84927 |
1301 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
14 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70147 |
1299 |
DA.PVG.1AV1-(D4Rat113-D4Kiru80)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
55.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84889 |
1301 |
DA/ZtmKini |
liver weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
liver mass |
male |
0 days
| 8 |
28.96 |
g/kg |
0.64 |
1.8 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
84933 |
1301 |
LEW/SsNHsd |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (0.1 ml) |
Cannon GW, et al., J Rheumatol 1993 Jan;20(1):7-11 |
joint integrity trait |
not specified |
77 days-105 days |
6 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
97068 |
1158 |
PVG.1AV1.DA-(D4Mgh17-D4Rat84)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 16 |
20.2 |
d |
2.98 |
11.9 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84910 |
1301 |
DA.PVG.1AV1-(D4Rat63-D4Rat84)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 9 |
17.0 |
d |
0.93 |
2.8 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84900 |
1301 |
F344/NHsd |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
10 |
30.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70149 |
1299 |
DA.F344-(D10Arb20-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70153 |
1299 |
DA.PVG.1AV1-(D4Rat155-Spr) |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
13.7 |
d |
0.43 |
1.5 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70198 |
1301 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 7 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70199 |
1301 |
DA/Bkl |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (0.1 ml) |
Cannon GW, et al., J Rheumatol 1993 Jan;20(1):7-11 |
joint integrity trait |
male |
70 days-105 days |
12 |
15.8 |
d |
3.3 |
11.43 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69553 |
1158 |
BBDR/Rhw |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
male |
66 days-126 days |
11 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69921 |
1241 |
BN/SsN |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
joint integrity trait |
both |
66 days-126 days |
13 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
immunized |
10 |
days |
variable |
|
|
69961 |
850 |
DA/Ztm |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
10 |
600.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69769 |
1162 |
DA/Ztm |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
14.2 |
d |
0.4 |
1.26 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69790 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
11 |
0.7 |
% |
1.6 |
5.31 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69801 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
71.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69711 |
1162 |
DA.PVG.1AV1-(D4Rat203-D4Mit22)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 10 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84879 |
1301 |
DA.PVG.1AV1-(D4Rat155-D4Rat113)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 9 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84875 |
1301 |
DA.PVG.1AV1-(D4Got126-D4Got136) |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 14 |
64.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84886 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
male |
0 days
| 24 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84465 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 15 |
93.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84469 |
1301 |
DA.PVG.1AV1-(D4Rat231-D4Mit12)/Kini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
13.3 |
d |
0.54 |
1.8 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84922 |
1301 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
male |
120 days-180 days |
13 |
540.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69762 |
1162 |
DA/Ztm |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
9 |
15.2 |
d |
0.2 |
0.6 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69782 |
1162 |
DA.F344-(D10Rat204-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
female |
63 days-126 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70155 |
1299 |
LEW.1AV1.DA-(D4Mgh17-D4Rat203)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 13 |
15.4 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70193 |
1301 |
DA.PVG.1AV1-(D4Rat155-Spr) |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
25.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70197 |
1301 |
BBDR/Rhw |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
male |
66 days-126 days |
11 |
30.6 |
null |
1.51 |
5.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69925 |
1241 |
DA.PVG.1AV1-(D4Rat62-D4Got136)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
75.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84882 |
1301 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
15 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70146 |
1299 |
DA.F344-(D10Rat204-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
9 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70154 |
1299 |
DA/Bkl |
post-insult time to onset of experimental arthritis |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
joint integrity trait |
both |
66 days-126 days |
105 |
15.0 |
d |
0.2 |
2.0 |
in vivo visual assessment |
0.0 |
immunized |
10 |
days |
variable |
|
|
68143 |
850 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 5 |
12.2 |
d |
0.18 |
0.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70196 |
1301 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 37 |
5.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70201 |
1301 |
ACI/SegHsd |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.25 mg/ml) and Freund's incomplete adjuvant (50 %) |
Dahlman I, et al., Hum Mol Genet 1999 Nov;8(12):2183-90. |
central nervous system integrity trait |
not specified |
70 days-145 days |
21 |
5.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69970 |
1279 |
BN/SsN |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
female |
66 days-126 days |
7 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69924 |
1241 |
BBDR/Rhw |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
female |
66 days-126 days |
13 |
31.7 |
null |
1.75 |
6.3 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69926 |
1241 |
BN/SsN |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
female |
66 days-126 days |
7 |
1.9 |
null |
0.68 |
1.8 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69928 |
1241 |
BN/SsN |
body weight loss |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
body mass |
both |
66 days-126 days |
13 |
0.0 |
% |
0.0 |
0.0 |
body weighing method |
0.0 |
immunized |
10 |
days |
variable |
(weight loss) |
|
69958 |
850 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
joint integrity trait |
both |
66 days-126 days |
105 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
immunized |
10 |
days |
variable |
|
|
69959 |
850 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
11 |
540.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69760 |
1162 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
10 |
660.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69770 |
1162 |
DA/Ztm |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
12 |
14.5 |
d |
0.5 |
1.73 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69777 |
1162 |
PVG.1AV1 |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
15 |
14.6 |
d |
0.4 |
1.55 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69778 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
11 |
15.4 |
d |
0.5 |
1.66 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69781 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69712 |
1162 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65 days-112 days |
22 |
15.8 |
d |
1.9 |
8.9 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69489 |
837 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65 days-112 days |
22 |
19.6 |
d |
2.22 |
10.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69493 |
837 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.1 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91 days-112 days |
0 |
69.0 |
% |
|
48.0 |
in vivo visual assessment |
0.0 |
|
0 |
|
visual observation |
|
|
69498 |
837 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
12 |
19.7 |
d |
2.48 |
8.6 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69376 |
837 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (15-22 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91 days-112 days |
13 |
69.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
68123 |
837 |
DA.PVG.1AV1-(D4Rat203-D4Got130)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84877 |
1301 |
DA.PVG.1AV1-(D4Rat155-D4Rat113)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 9 |
14.4 |
d |
0.73 |
2.2 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84915 |
1301 |
DA.PVG.1AV1-(D4Rat62-D4Got136)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
15.4 |
d |
0.66 |
2.3 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84921 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
male |
0 days
| 24 |
14.6 |
d |
1.39 |
6.8 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84467 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 6 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84470 |
1301 |
DA.PVG.1AV1-(D4Rat113-D4Kiru80)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
17.2 |
d |
1.63 |
5.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84925 |
1301 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
16.4 |
d |
0.8 |
2.53 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69791 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
14 |
2.8 |
% |
1.0 |
3.74 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69799 |
1162 |
DA/ZtmKini |
plasma orosomucoid 1 level |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
orosomucoid 1 amount |
male |
0 days
| 8 |
419.0 |
mg/l |
82.02 |
232.0 |
radial immunodiffusion assay |
0.0 |
|
0 |
|
|
|
|
84929 |
1301 |
DA.PVG.1AV1-(D4Rat203-D4Mit22)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 10 |
12.6 |
d |
0.32 |
1.0 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84918 |
1301 |
PVG.1AV1.DA-(D4Mgh17-D4Rat84)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 16 |
68.8 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84872 |
1301 |
DA.PVG.1AV1-(D4Rat63-D4Rat84)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 9 |
22.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84876 |
1301 |
DA.PVG.1AV1-(D4Mit22-D4Rat84)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84880 |
1301 |
LEW.1AV1.DA-(D4Mgh17-D4Rat203)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 13 |
16.0 |
d |
0.0 |
0.0 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84903 |
1301 |
LEW.1AV1/Kini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70189 |
1301 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (0.1 ml) |
Cannon GW, et al., J Rheumatol 1993 Jan;20(1):7-11 |
joint integrity trait |
male |
77 days-105 days |
12 |
83.3 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69552 |
1158 |
DA/Ztm |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.25 mg/ml) and Freund's incomplete adjuvant (50 %) |
Dahlman I, et al., Hum Mol Genet 1999 Nov;8(12):2183-90. |
central nervous system integrity trait |
not specified |
70 days-145 days |
36 |
72.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69969 |
1279 |
BN/SsN |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
male |
66 days-126 days |
13 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69923 |
1241 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
13 |
22.5 |
d |
3.58 |
12.9 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69492 |
837 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91 days-112 days |
0 |
89.0 |
% |
|
33.0 |
in vivo visual assessment |
0.0 |
|
0 |
|
visual observation |
|
|
69497 |
837 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (0.1 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
0 |
22.5 |
d |
|
12.9 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69500 |
837 |
DA/Ztm |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
male |
120 days-180 days |
9 |
590.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69761 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
14.3 |
d |
0.3 |
1.12 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69780 |
1162 |
DA/Ztm |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
12 |
13.4 |
% |
1.4 |
4.85 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69798 |
1162 |
DA/Ztm |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
10 |
22.8 |
% |
1.1 |
3.48 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69809 |
1162 |
DA.PVG.1AV1-(D4Got126-D4Rat203)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 7 |
43.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84881 |
1301 |
DA.PVG.1AV1-(D4Mit22-D4Rat84)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 12 |
13.0 |
d |
0.38 |
1.3 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84919 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
female |
0 days
| 24 |
91.7 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84466 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 6 |
16.3 |
d |
0.94 |
2.3 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84472 |
1301 |
DA/Bkl |
body weight loss |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
body mass |
both |
66 days-126 days |
105 |
19.0 |
% |
0.49 |
5.0 |
body weighing method |
0.0 |
immunized |
10 |
days |
variable |
(weight loss) |
|
69960 |
850 |
BN/SsN |
calculated serum anti-rat type 2 collagen autoantibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood autoantibody amount |
both |
66 days-126 days |
13 |
2.0 |
null |
0.55 |
2.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69965 |
850 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
65 days-112 days |
21 |
21.9 |
d |
2.47 |
11.3 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69494 |
837 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (0.1 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
0 |
10.1 |
d |
|
9.5 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69502 |
837 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
13 |
15.5 |
d |
0.2 |
0.72 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69783 |
1162 |
DA/Ztm |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
male |
120 days-200 days |
9 |
7.5 |
% |
2.1 |
6.3 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69802 |
1162 |
DA.F344-(D10Arb20-D10Arb22)/Arb |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70152 |
1299 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 7 |
12.4 |
d |
0.49 |
1.3 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70200 |
1301 |
BBDR/Rhw |
percentage of study population developing chronic experimental arthritis during a period of time |
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
joint integrity trait |
female |
66 days-126 days |
13 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69922 |
1241 |
BN/SsN |
calculated serum anti-rat type 2 collagen autoantibody titer |
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg) |
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50 |
blood autoantibody amount |
male |
66 days-126 days |
13 |
1.3 |
null |
0.28 |
1.0 |
enzyme linked immunosorbent assay |
0.0 |
|
0 |
|
|
titer |
|
69927 |
1241 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 27 |
96.3 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70188 |
1301 |
DA.PVG.1AV1-(D4Rat113-D4Rat62)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 18 |
89.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84892 |
1301 |
F344/NHsd |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. |
joint integrity trait |
male |
63 days-126 days |
10 |
20.0 |
% |
|
|
in vivo visual assessment |
3024000.0 |
|
0 |
|
|
|
|
70148 |
1299 |
DA/Bkl |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (0.1 ml) |
Cannon GW, et al., J Rheumatol 1993 Jan;20(1):7-11 |
joint integrity trait |
male |
77 days-105 days |
10 |
50.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69551 |
1158 |
DA.PVG-(D4Rat141-D4Mgh11) |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 30 |
10.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70191 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 5 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70192 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 27 |
14.0 |
d |
1.06 |
5.5 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70194 |
1301 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
91 days-112 days |
22 |
82.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
visual observation |
|
|
69487 |
837 |
DA/ZtmKini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (0.09 ug/g) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
0 |
20.0 |
d |
|
8.5 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69501 |
837 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
experimental autoimmune encephalomyelitis duration |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
13 |
10.1 |
d |
2.63 |
9.5 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69377 |
837 |
DA/Ztm |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
10 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69722 |
1162 |
DA.PVG.1AV1-(D4Mgh17-D4Rat56) |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
11 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69713 |
1162 |
DA/Ztm |
percentage of study population developing experimental arthritis during a period of time |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
male |
120 days-200 days |
9 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69714 |
1162 |
DA.PVG.1AV1-(D4Rat113-D4Rat62)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 18 |
14.8 |
d |
0.75 |
3.2 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84926 |
1301 |
DA.PVG.1AV1-(D4Rat63-D4Rat203)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
14.0 |
d |
0.42 |
1.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84917 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
female |
0 days
| 24 |
14.6 |
d |
0.63 |
3.1 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84468 |
1301 |
DA/ZtmKini |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 15 |
14.9 |
d |
1.52 |
5.9 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84471 |
1301 |
DA/Bkl |
calculated serum anti-rat type 2 collagen autoantibody titer |
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) |
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89 |
blood autoantibody amount |
both |
66 days-126 days |
105 |
15.0 |
null |
0.59 |
6.0 |
enzyme linked immunosorbent assay |
0.0 |
immunized |
10 |
days |
variable |
titer |
|
69963 |
850 |
DA.PVG.1AV1-(D4Rat63-D4Rat203)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
45.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84878 |
1301 |
DA.PVG.1AV1-(D17Rat8-D17Rat37)/Kini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (30 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
male |
91 days-112 days |
21 |
76.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
visual observation |
|
|
69488 |
837 |
DA/ZtmKini |
post-insult time to onset of experimental autoimmune encephalomyelitis |
myelin oligodendrocyte glycoprotein (15-20 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
65 days-112 days |
12 |
14.8 |
d |
2.4 |
8.3 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69491 |
837 |
PVG.1AV1 |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
15 |
250.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69757 |
1162 |
DA.PVG.1AV1-(D4Rat155-Spr) |
serum orosomucoid 1 level |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
orosomucoid 1 amount |
both |
120 days-180 days |
14 |
660.0 |
mg/l |
|
|
radial immunodiffusion assay |
0.0 |
|
0 |
|
radial immunodiffusion assay |
|
blood alpha-1-acid glycoprotein amount |
69759 |
1162 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
post-insult time to onset of experimental arthritis |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
joint integrity trait |
both |
120 days-200 days |
14 |
17.6 |
d |
0.8 |
2.99 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
69779 |
1162 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
maximum body weight loss to initial body weight ratio |
type II collagen (500 ug) and Freund's incomplete adjuvant (100 ul) |
Backdahl L, et al., Arthritis Rheum 2003 Feb;48(2):551-9. |
body mass |
both |
120 days-200 days |
10 |
14.6 |
% |
1.8 |
5.69 |
body weighing method |
0.0 |
|
0 |
|
|
|
|
69810 |
1162 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune encephalomyelitis during a period of time |
myelin oligodendrocyte glycoprotein (15-22 ug) and Freund's incomplete adjuvant (100 ul) |
Stridh P, et al., PLoS One. 2010 Sep 15;5(9):e12716. |
central nervous system integrity trait |
female |
91 days-112 days |
12 |
92.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
68122 |
837 |
DA.PVG.1AV1-(D4Rat63-D4Rat203) |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 37 |
14.0 |
d |
0.0 |
0.0 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70202 |
1301 |
PVG.1AV1/Kini |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 29 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70190 |
1301 |
DA.PVG-(D4Rat141-D4Mgh11) |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 30 |
31.7 |
d |
1.86 |
10.2 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
70195 |
1301 |
DA.PVG.1AV1-(D4Rat113-D4Kiru96)/Kiru |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 8 |
100.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84884 |
1301 |
DA/ZtmKini |
spleen weight to body weight ratio |
Freund's incomplete adjuvant (200 ul) (for 10 days) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
spleen mass |
male |
0 days
| 8 |
0.18 |
% |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
0 |
|
|
|
|
84931 |
1301 |
DA.PVG.1AV1-(D4Rat203-D4Got130)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 11 |
14.9 |
d |
1.03 |
3.4 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84916 |
1301 |
DA.PVG.1AV1-(D4Got126-D4Rat203)/Kiru |
post-insult time to onset of experimental arthritis |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 7 |
12.7 |
d |
0.45 |
1.2 |
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84920 |
1301 |
DA.PVG.1AV1-(D4Rat155-D4Rat84) |
percentage of study population developing experimental arthritis during a period of time |
Freund's incomplete adjuvant (200 ul) |
Ribbhammar U, et al., Hum Mol Genet 2003 Sep 1;12(17):2087-96. |
joint integrity trait |
both |
0 days
| 7 |
0.0 |
% |
|
|
in vivo visual assessment |
0.0 |
|
0 |
|
|
|
|
84874 |
1301 |