Phenominer Database Results (15 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Clinical Measurement Notes Record ID Study ID
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 5 30.4 % 2.7 6.04 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 105 days remodeling/total ratio 69146 950
F344/NRrrc malignant liver tumor number N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 16 2.2 null 0.2 0.8 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days check malignant 69153 950
F344/NRrrc volume of liver occupied by tumorous lesions as percentage of total liver volume N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait female 0 days 3 8.92 % 2.85 4.94 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 68619 950
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy then 5-bromo-2'-deoxyuridine (50 mg/kg) (for 2 hours) Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 5 1070.0 % 143.0 319.76 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 69143 950
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 3 19.2 % 2.8 4.85 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 69148 950
F344/NRrrc percentage of study population developing benign liver tumors during a period of time N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 16 100.0 % 5.4 21.6 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days benign liver tumor incidence 69150 950
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 5 15.1 % 1.1 2.46 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 224 days remodeling/total ratio 69147 950
F344/NRrrc ratio of apoptotic bodies to intact tumor cells in remodelling liver tumorous lesions N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and controlled 2-acetamidofluorene content diet (0.02 %) then partial hepatectomy De Miglio MR, et al., Int J Cancer 2003 May 20;105(1):70-5. liver integrity trait not specified 0 days 5 1.51 % 0.07 0.16 ex vivo light microscopy with immunohistochemistry and digital image analysis 0.0 0 84787 1603
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 3 40.6 % 5.4 9.35 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 224 days remodeling/total ratio 69149 950
F344/NRrrc percentage of study population developing malignant liver tumors during a period of time N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 16 100.0 % 5.4 21.6 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days check malignant 69152 950
F344/NRrrc benign liver tumor number N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 16 22.3 null 2.0 8.0 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 490 days 69151 950
F344/NRrrc liver tumorous lesion number N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait female 0 days 3 1424.0 null 242.0 419.16 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days 68617 950
F344/NRrrc ratio of apoptotic bodies to intact tumor cells in nonremodelling liver tumorous lesions N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and controlled 2-acetamidofluorene content diet (0.02 %) then partial hepatectomy De Miglio MR, et al., Int J Cancer 2003 May 20;105(1):70-5. liver integrity trait not specified 0 days 5 1.25 % 0.05 0.11 ex vivo light microscopy with immunohistochemistry and digital image analysis 0.0 0 84785 1603
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled protein content diet (for 15 days) and 2-acetamidofluorene (0.02 %) (for 15 days) then partial hepatectomy (for 202.5 days) De Miglio MR, et al., Int J Cancer 2004 Aug 10;111(1):9-16. liver integrity trait male 0 days 10 19.0 % ex vivo light microscopy with digital image analysis liver 0.0 224 days 70204 1302
F344/NRrrc liver remodeling tumorous lesion number to liver total tumorous lesion number ratio N-nitrosodiethylamine (150 mg/kg) then controlled 2-acetamidofluorene content diet (0.02 %) (for 14 days) then partial hepatectomy Pascale RM, et al., Carcinogenesis. 1996 Aug;17(8):1765-8. liver integrity trait male 0 days 9 13.8 % 0.8 2.4 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethtlamine injection 56 days remodeling/total ratio 69145 950