Phenominer Database Results (18 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
SHR/NCrl sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 100.0 % 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 55378 522
SHR/NCrl sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 9 99.56 % 0.34 1.01 wire myography using a Digi-Med tissue force analysis system with force transducer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 55381 522
SHR/NCrl sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 100.0 % 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 55967 522
SHR/NCrl sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 7 100.0 % 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 55973 522
SHR/NCrl logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 7 -8.58 null 0.12 0.32 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56002 522
SHR/NCrl sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 9 99.44 % 0.44 1.33 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56196 522
SHR/NCrl sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 10 96.9 % 1.87 5.92 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56202 522
SHR/NCrl concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 9 0.05 10E-7mol/l 0.01 0.02 wire myography using a Digi-Med tissue force analysis system with force transducer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 56814 522
SHR/NCrl concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 7 0.03 10E-7mol/l 0.01 0.03 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56701 522
SHR/NCrl logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 -8.36 null 0.09 0.26 wire myography using a Digi-Med tissue force analysis system with force transducer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 55498 522
SHR/NCrl concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 0.04 10E-7mol/l 0.01 0.03 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56262 522
SHR/NCrl concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 10 0.28 10E-7mol/l 0.18 0.57 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56268 522
SHR/NCrl logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 -8.58 null 0.14 0.39 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 55487 522
SHR/NCrl logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 9 -8.34 null 0.06 0.17 wire myography using a Digi-Med tissue force analysis system with force transducer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 55501 522
SHR/NCrl logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 7 -8.77 null 0.21 0.54 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56008 522
SHR/NCrl concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 7 0.04 10E-7mol/l 0.01 0.03 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 56695 522
SHR/NCrl logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 10 -7.97 null 0.17 0.54 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Dyets 55493 522
SHR/NCrl concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 0.05 10E-7mol/l 0.01 0.04 wire myography using a Digi-Med tissue force analysis system with force transducer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 56811 522