| LE/BluGill |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
14 |
-8.28 |
null |
0.06 |
0.24 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
55120 |
522 |
| LE/BluGill |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
14 |
-8.48 |
null |
0.06 |
0.24 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
55116 |
522 |
| LE/BluGill |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
13 |
99.54 |
% |
0.33 |
1.2 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57121 |
522 |
| LE/BluGill |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
13 |
0.03 |
10E-7mol/l |
0.0 |
0.01 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
56457 |
522 |
| LE/BluGill |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
14 |
0.04 |
10E-7mol/l |
0.01 |
0.02 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
56767 |
522 |
| LE/BluGill |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
14 |
100.0 |
% |
0.0 |
0.0 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
56856 |
522 |
| LE/BluGill |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
11 |
-8.48 |
null |
0.13 |
0.41 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
55353 |
522 |
| LE/BluGill |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
14 |
99.21 |
% |
0.53 |
1.97 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
56860 |
522 |
| LE/BluGill |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
12 |
98.25 |
% |
1.75 |
6.06 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57125 |
522 |
| LE/BluGill |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
13 |
-8.65 |
null |
0.07 |
0.24 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
55349 |
522 |
| LE/BluGill |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
11 |
0.05 |
10E-7mol/l |
0.01 |
0.03 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
56461 |
522 |
| LE/BluGill |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
14 |
0.08 |
10E-7mol/l |
0.02 |
0.08 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
56771 |
522 |