Phenominer Database Results (168 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
SS.BN-(D12Arb13-D12Rat79)/Mcwi partial pressure of blood carbon dioxide (Pco2) controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood gas amount female 82.0 days-99.0 days 9 25.78 mmHg 0.57 1.7 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 17221 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82.0 days-99.0 days 9 0.06 null 0.0 0.01 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19759 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82.0 days-99.0 days 9 0.05 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19764 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 15 119.35 % 2.9 11.24 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53821 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 49.27 ml/min 2.43 8.4 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18652 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 434.17 beats/min 16.01 45.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17482 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount male 77.0 days-91.0 days 14 9.56 mg/dl 0.1 0.39 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36610 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82.0 days-99.0 days 10 53.17 mmHg 1.44 4.55 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 20449 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass male 49.0 days-63.0 days 15 198.2 g 4.2 16.3 whole body digital scale Moms and pups used in studies were fed Teklad 49494 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data body mass female 49.0 days-63.0 days 15 163.2 g 2.0 7.9 whole body digital scale Moms and pups used in studies were fed Teklad 49502 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 15 130.03 % 5.02 19.45 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 54394 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount female 77.0 days-91.0 days 10 38.7 U/l 2.52 7.97 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40704 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77.0 days-91.0 days 14 4.51 mmol/l 0.2 0.75 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38052 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait male 77.0 days-91.0 days 14 59.86 fl 0.96 3.58 automated blood cell counting method Moms and pups used in studies were fed Teklad 38731 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49.0 days-63.0 days 15 5.82 g/kg 0.12 0.48 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 45592 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 33.9 % 5.61 20.99 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48517 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 8 10.34 ml/min/kg 0.51 1.44 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57786 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait male 77.0 days-91.0 days 8 0.05 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 58475 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass female 77.0 days-91.0 days 10 0.37 null 0.02 0.06 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 58723 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 14 136.86 mmHg 4.19 15.69 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45719 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 13 7.73 ml/min/g 0.51 1.84 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 44708 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 41.68 % 4.12 15.43 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47063 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 48.49 % 4.72 17.67 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47067 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 12 5.81 mmHg 0.1 0.35 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47187 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 12 267.84 beats/min 40.9 141.69 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45134 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 13 56.52 mmHg 3.21 11.59 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46407 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 11 50.68 mmHg 8.4 27.85 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45256 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 0.37 ml 0.02 0.07 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 15223 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 106.25 % 3.64 12.62 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 54057 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 12 118.83 breaths/min 6.66 23.06 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 14784 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 124.43 mmHg 3.67 10.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14309 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in partial pressure of blood carbon dioxide controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount male 82.0 days-99.0 days 9 -5.01 mmHg 0.58 1.74 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19609 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait male 82.0 days-99.0 days 10 7.53 null 0.01 0.03 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17022 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount female 77.0 days-91.0 days 10 114.0 U/l 8.91 28.17 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36369 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount female 77.0 days-91.0 days 10 89.7 mg/dl 3.09 9.76 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37087 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount male 82.0 days-99.0 days 9 -50.07 mmHg 3.27 9.81 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19438 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 43.15 ml/min 2.38 8.25 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 20198 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 13 10.36 % 2.48 8.95 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 49684 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 13 103.49 mmHg 5.02 18.08 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49878 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 14 53.43 mmHg 3.22 12.04 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49987 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean corpuscular volume controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte size trait female 77.0 days-91.0 days 10 60.38 fl 0.8 2.53 automated blood cell counting method Moms and pups used in studies were fed Teklad 38735 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77.0 days-91.0 days 10 53.86 % 1.7 5.38 automated blood cell counting method Moms and pups used in studies were fed Teklad 38981 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount male 77.0 days-91.0 days 14 145.29 mmol/l 0.91 3.41 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39374 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount female 77.0 days-91.0 days 10 64.9 U/l 2.73 8.63 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42760 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77.0 days-91.0 days 10 32.03 g/dl 0.11 0.35 automated blood cell counting method Moms and pups used in studies were fed Teklad 39767 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity female 77.0 days-91.0 days 10 0.65 x 1000 cells/ul 0.09 0.28 automated blood cell counting method Moms and pups used in studies were fed Teklad 43214 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity male 77.0 days-91.0 days 10 55.21 % 1.97 6.24 microhematocrit tube assay with visual assessment Moms and pups used in studies were fed Teklad 59243 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 10 0.15 mmHg x min x kg x ml-1 0.01 0.03 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 59537 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass female 77.0 days-91.0 days 10 1.49 g/kg 0.05 0.17 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 59647 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77.0 days-91.0 days 14 16.71 g/dl 0.65 2.42 automated blood cell counting method Moms and pups used in studies were fed Teklad 37954 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77.0 days-91.0 days 10 4.26 mmol/l 0.11 0.34 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38056 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount female 77.0 days-91.0 days 10 159.6 mg/dl 8.38 26.5 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38520 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity female 77.0 days-91.0 days 10 0.05 x 1000 cells/ul 0.02 0.06 automated blood cell counting method Moms and pups used in studies were fed Teklad 41637 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 250.09 beats/min 11.1 41.53 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47572 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 62.11 % 10.41 38.95 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48742 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 8 8.38 ml/min/kg 0.35 0.99 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57584 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart right ventricle weight to left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data heart right ventricle mass male 77.0 days-91.0 days 10 0.4 null 0.03 0.1 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 58719 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 14 14.82 ml/min/g 0.51 1.93 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46643 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 14 12.9 ml/min/g 0.79 2.95 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46639 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 0.47 ml 0.02 0.09 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 15219 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 15 117.97 breaths/min 3.71 14.38 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 14780 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 %change=VE during 2-3 min hypoxia/control during standard conditions 152.04 % 5.31 20.57 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13666 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 12 113.53 % 8.09 28.04 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53824 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 117.95 % 3.6 13.93 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53953 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 118.68 % 3.63 12.58 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 53956 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in partial pressure of blood carbon dioxide controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood carbon dioxide amount female 82.0 days-99.0 days 9 -6.14 mmHg 1.06 3.17 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19614 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood pH controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood acidity-alkalinity balance trait female 82.0 days-99.0 days 9 7.51 null 0.01 0.02 automated blood gas analysis using a Bayer analyzer Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17027 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum alkaline phosphatase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alkaline phosphatase amount male 77.0 days-91.0 days 14 179.79 U/l 17.52 65.54 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36365 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.45 beats/min 10.38 31.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17477 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum calcium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood calcium amount female 77.0 days-91.0 days 10 9.57 mg/dl 0.1 0.32 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36614 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 12 123.6 breaths/min 10.34 35.82 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18255 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82.0 days-99.0 days 15 0.26 degrees C 0.17 0.67 digital rectal thermometry Moms and pups used in studies were fed Teklad 20295 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82.0 days-99.0 days 12 0.18 degrees C 0.2 0.69 digital rectal thermometry Moms and pups used in studies were fed Teklad 20299 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 14 1097.74 s 40.71 152.31 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50213 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount male 77.0 days-91.0 days 14 19.5 mmol/l 0.91 3.39 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42048 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount male 77.0 days-91.0 days 14 3.7 g/dl 0.09 0.33 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42219 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77.0 days-91.0 days 14 19.34 pg 0.28 1.07 automated blood cell counting method Moms and pups used in studies were fed Teklad 42531 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean corpuscular hemoglobin controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77.0 days-91.0 days 10 19.32 pg 0.21 0.67 automated blood cell counting method Moms and pups used in studies were fed Teklad 42535 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data erythrocyte quantity female 77.0 days-91.0 days 8 56.23 % 0.79 2.23 microhematocrit tube assay with visual assessment Moms and pups used in studies were fed Teklad 59247 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount male 77.0 days-91.0 days 14 9.13 mg/dl 0.18 0.67 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37580 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount female 77.0 days-91.0 days 10 23.4 mg/dl 1.88 5.93 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40818 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity male 77.0 days-91.0 days 14 6.01 x 1000 cells/ul 0.56 2.11 automated blood cell counting method Moms and pups used in studies were fed Teklad 40912 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi total white blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data leukocyte quantity female 77.0 days-91.0 days 10 5.34 x 1000 cells/ul 0.64 2.01 automated blood cell counting method Moms and pups used in studies were fed Teklad 40916 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi calculated pulmonary vascular resistance normalized to body weight controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 8 0.14 mmHg x min x kg x ml-1 0.01 0.03 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 59533 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood hemoglobin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount female 77.0 days-91.0 days 10 17.25 g/dl 0.51 1.63 automated blood cell counting method Moms and pups used in studies were fed Teklad 37958 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait female 77.0 days-91.0 days 10 22.9 mmol/l 0.57 1.79 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38251 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity female 77.0 days-91.0 days 10 4.31 x 1000 cells/ul 0.51 1.62 automated blood cell counting method Moms and pups used in studies were fed Teklad 41493 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum glucose level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood glucose amount male 77.0 days-91.0 days 14 153.43 mg/dl 4.08 15.27 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38516 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass male 49.0 days-63.0 days 15 1.15 g 0.03 0.12 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 45391 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 14 255.94 beats/min 9.61 35.95 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47568 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 30.39 % 6.29 23.54 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48513 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 70.53 % 6.49 24.26 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48746 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 9 29.04 ml/min/kg 2.45 7.35 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57989 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 8 0.44 null 0.03 0.1 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 58103 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49.0 days-63.0 days 15 5.93 g/kg 0.17 0.66 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 45600 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 6 11.43 IU/g 0.72 1.77 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 45697 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 13 136.71 mmHg 5.52 19.91 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45715 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 13 273.2 beats/min 40.93 147.57 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45138 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 12 0.18 IU/g 0.06 0.2 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47432 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in tidal volume controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 113.11 % 3.26 12.62 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 54054 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 121.05 mmHg 3.21 9.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14304 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 %change=VE during 2-3 min hypoxia/control during standard conditions 137.06 % 8.57 29.68 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13670 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount male 77.0 days-91.0 days 14 5.91 g/dl 0.11 0.41 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36948 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum total cholesterol level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood cholesterol amount male 77.0 days-91.0 days 14 92.5 mg/dl 2.53 9.46 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37083 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 62.79 ml/min 3.82 14.79 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18648 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait male 82.0 days-99.0 days 15 128.13 breaths/min 4.86 18.82 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 18251 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi minute ventilation controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 55.63 ml/min 3.32 12.85 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 20194 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82.0 days-99.0 days 9 56.77 mmHg 1.99 5.98 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 20454 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 14 795.77 s 51.48 192.61 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49285 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 14 7.8 % 2.44 9.12 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 49688 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 12 100.35 mmHg 12.99 45.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49874 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 14 51.29 mmHg 4.18 15.63 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49983 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 1130.56 s 41.48 155.2 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50217 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum albumin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood albumin amount female 77.0 days-91.0 days 10 4.03 g/dl 0.06 0.19 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42223 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount male 77.0 days-91.0 days 14 106.79 mmol/l 0.49 1.85 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39103 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77.0 days-91.0 days 14 8.61 x 10E6 cells/ul 0.24 0.9 automated blood cell counting method Moms and pups used in studies were fed Teklad 39223 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum aspartate aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood aspartate transaminase amount male 77.0 days-91.0 days 13 85.0 U/l 4.14 14.92 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42756 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount male 77.0 days-91.0 days 14 0.27 mg/dl 0.02 0.09 automated plasma creatinine analysis Moms and pups used in studies were fed Teklad 39562 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi plasma creatinine level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood creatinine amount female 77.0 days-91.0 days 10 0.33 mg/dl 0.03 0.08 automated plasma creatinine analysis Moms and pups used in studies were fed Teklad 39566 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity male 77.0 days-91.0 days 14 0.36 x 1000 cells/ul 0.07 0.26 automated blood cell counting method Moms and pups used in studies were fed Teklad 39660 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood monocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data monocyte quantity female 77.0 days-91.0 days 10 0.34 x 1000 cells/ul 0.07 0.22 automated blood cell counting method Moms and pups used in studies were fed Teklad 39664 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean corpuscular hemoglobin concentration controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood hemoglobin amount male 77.0 days-91.0 days 14 32.41 g/dl 0.18 0.67 automated blood cell counting method Moms and pups used in studies were fed Teklad 39763 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass male 77.0 days-91.0 days 10 238.5 g 4.9 15.4 whole body digital scale Moms and pups used in studies were fed Teklad 59048 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount male 77.0 days-91.0 days 14 2.21 g/dl 0.05 0.18 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40536 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi plasma anion gap controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data ion homeostasis trait male 77.0 days-91.0 days 14 23.43 mmol/l 0.8 3.01 standard blood chemistry panel Moms and pups used in studies were fed Teklad 38247 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood lymphocyte count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data lymphocyte quantity male 77.0 days-91.0 days 14 4.93 x 1000 cells/ul 0.47 1.75 automated blood cell counting method Moms and pups used in studies were fed Teklad 41489 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood eosinophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data eosinophil quantity male 77.0 days-91.0 days 13 0.01 x 1000 cells/ul 0.01 0.03 automated blood cell counting method Moms and pups used in studies were fed Teklad 41633 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart wet weight controlled air oxygen content (12 %) (for 14 days) PhysGen Cardiac data heart mass female 49.0 days-63.0 days 15 0.97 g 0.03 0.12 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 45395 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 13 131.21 mmHg 5.59 20.15 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48610 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi methylene blue metabolism-surface area product without auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 9 12.83 ml/min/kg 0.82 2.46 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57790 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait male 82.0 days-99.0 days 15 37.75 degrees C 0.08 0.31 digital rectal thermometry Moms and pups used in studies were fed Teklad 16558 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi fractional change in blood vessel diameter per unit change in intravascular pressure controlled air oxygen content (12 %) (for 14 days) then Kreb's solution perfusate (between 0.2 and 0.2 hours) PhysGen Lung data blood vessel distensibility trait female 77.0 days-91.0 days 10 0.04 mmHg-1 0.0 0.01 fluid-filled catheter with pressure transducer in isolated perfused lung Moms and pups used in studies were fed Teklad 58479 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait male 77.0 days-91.0 days 7 1.38 mg/kg 0.29 0.78 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 58892 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 13 5.8 ml/min/g 0.47 1.7 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 44704 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 14 5.52 mmHg 0.18 0.68 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47183 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 102.49 % 15.94 59.64 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48285 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 13 46.97 mmHg 6.46 23.28 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45260 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi partial pressure of blood carbon dioxide (Pco2) controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood gas amount male 82.0 days-99.0 days 10 24.78 mmHg 1.28 4.05 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 17216 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait male 82.0 days-99.0 days 15 0.49 ml 0.02 0.09 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13909 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi tidal volume controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data pulmonary ventilation trait female 82.0 days-99.0 days 12 0.41 ml 0.02 0.08 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 13913 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum total protein level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood total protein amount female 77.0 days-91.0 days 10 6.19 g/dl 0.1 0.31 standard blood chemistry panel Moms and pups used in studies were fed Teklad 36952 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in partial pressure of blood oxygen controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data blood oxygen amount female 82.0 days-99.0 days 9 -40.93 mmHg 3.13 9.38 automated blood gas analysis using a Bayer analyzer Moms and pups used in studies were fed Teklad 19443 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 14 778.86 s 50.73 189.8 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49289 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum bicarbonate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bicarbonate amount female 77.0 days-91.0 days 10 18.2 mmol/l 0.94 2.97 standard blood chemistry panel Moms and pups used in studies were fed Teklad 42052 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi hematocrit controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity male 77.0 days-91.0 days 14 51.74 % 2.06 7.71 automated blood cell counting method Moms and pups used in studies were fed Teklad 38977 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum chloride level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood chloride amount female 77.0 days-91.0 days 10 106.9 mmol/l 0.81 2.56 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39107 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi red blood cell count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data erythrocyte quantity female 77.0 days-91.0 days 10 8.91 x 10E6 cells/ul 0.21 0.66 automated blood cell counting method Moms and pups used in studies were fed Teklad 39227 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum sodium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood sodium amount female 77.0 days-91.0 days 10 143.8 mmol/l 1.02 3.22 standard blood chemistry panel Moms and pups used in studies were fed Teklad 39378 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in respiration rate controlled air oxygen content (12 %) (between 0 and 0.1 hours) PhysGen Respiratory data respiratory function trait female 82.0 days-99.0 days 12 116.96 % 8.97 31.07 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 54397 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi blood neutrophil count controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data neutrophil quantity male 77.0 days-91.0 days 14 0.72 x 1000 cells/ul 0.1 0.37 automated blood cell counting method Moms and pups used in studies were fed Teklad 43210 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi dose of methacholine at which pulmonary conductance is half its pretreatment value controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) PhysGen Lung data pulmonary ventilation trait female 77.0 days-91.0 days 8 1.15 mg/kg 0.26 0.73 stop flow air displacement plethysmography Moms and pups used in studies were fed Teklad 58896 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi body weight controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data body mass female 77.0 days-91.0 days 10 176.4 g 3.1 10.0 whole body digital scale Moms and pups used in studies were fed Teklad 59052 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum globulin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood globulin amount female 77.0 days-91.0 days 10 2.16 g/dl 0.04 0.13 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 Moms and pups used in studies were fed Teklad 40540 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum alanine aminotransferase activity level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood alanine transaminase amount male 77.0 days-91.0 days 13 51.62 U/l 2.03 7.31 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40700 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum phosphate level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood phosphate amount female 77.0 days-91.0 days 10 8.65 mg/dl 0.39 1.24 standard blood chemistry panel Moms and pups used in studies were fed Teklad 37584 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum urea nitrogen level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood urea nitrogen amount male 77.0 days-91.0 days 14 19.93 mg/dl 0.68 2.53 standard blood chemistry panel Moms and pups used in studies were fed Teklad 40814 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi lung dry weight to body weight ratio controlled air oxygen content (12 %) (for 14 days) PhysGen Lung data lung mass male 77.0 days-91.0 days 10 1.18 g/kg 0.04 0.12 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 59643 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount male 77.0 days-91.0 days 14 0.1 mg/dl 0.0 0.0 standard blood chemistry panel Moms and pups used in studies were fed Teklad 41854 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi serum total bilirubin level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood bilirubin amount female 77.0 days-91.0 days 10 0.1 mg/dl 0.0 0.0 standard blood chemistry panel Moms and pups used in studies were fed Teklad 41858 401
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 12 131.2 mmHg 4.31 14.92 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48614 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi methylene blue metabolism-surface area product after auto-oxidation controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) PhysGen Lung data pulmonary blood flow trait female 77.0 days-91.0 days 9 11.16 ml/min/kg 0.64 1.93 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57588 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi FAPGG metabolism-surface area product controlled air oxygen content (12 %) (for 14 days) then FAPGG (0.6 mmol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 8 22.47 ml/min/kg 1.67 4.72 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 57985 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi body temperature controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data body temperature trait female 82.0 days-99.0 days 12 37.88 degrees C 0.19 0.67 digital rectal thermometry Moms and pups used in studies were fed Teklad 16562 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi methylene blue to FAPGG metabolism-surface area product ratio controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) PhysGen Lung data pulmonary blood flow trait male 77.0 days-91.0 days 8 0.47 null 0.03 0.08 isolated perfused lung vascular effluent collection Moms and pups used in studies were fed Teklad 58099 526
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 6 11.83 IU/g 0.85 2.09 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 45703 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 14 post-ischemic value/pre-ischemic value x 100% 90.27 % 16.16 60.48 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48281 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 11 58.34 mmHg 6.63 22.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46403 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 12 0.23 IU/g 0.06 0.19 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47424 461