Phenominer Database Results (86 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70.0 days-84.0 days 2 34.0 cm 0.0 0.0 in vivo ruler method 63665 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass female 70.0 days-84.0 days 2 0.12 g 0.0 0.01 digital scale post excision weight measurement 63275 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass male 70.0 days-84.0 days 2 1.0 g 0.05 0.06 digital scale post excision weight measurement 63340 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass male 70.0 days-84.0 days 2 0.83 g 0.03 0.05 digital scale post excision weight measurement 63412 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass female 70.0 days-84.0 days 2 174.5 g 5.5 7.78 whole body digital scale 63593 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 1 -6.97 null wire myography using a Digi-Med tissue force analysis system with force transducer 62815 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass female 70.0 days-84.0 days 2 174.5 g 5.5 7.78 whole body digital scale 62908 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait female 70.0 days-84.0 days 2 57.3 fl 0.2 0.28 automated blood cell counting method 60746 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount female 70.0 days-84.0 days 2 99.5 mmol/l 1.5 2.12 standard blood chemistry panel 62294 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount female 70.0 days-84.0 days 2 157.0 mg/dl 12.0 16.97 standard blood chemistry panel 62458 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount male 70.0 days-84.0 days 1 18.0 mg/dl standard blood chemistry panel 60145 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount male 70.0 days-84.0 days 1 9.8 mg/dl standard blood chemistry panel 60217 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass female 70.0 days-84.0 days 2 0.61 g 0.02 0.03 digital scale post excision weight measurement 63419 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70.0 days-84.0 days 1 0.93 g/mg wire myography using a Digi-Med tissue force analysis system with force transducer 63129 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70.0 days-84.0 days 2 0.85 g/mg 0.07 0.1 wire myography using a Digi-Med tissue force analysis system with force transducer 63135 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70.0 days-84.0 days 1 -7.47 null wire myography using a Digi-Med tissue force analysis system with force transducer EC50 value is moles/liter 63059 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70.0 days-84.0 days 1 43.3 % automated blood cell counting method 60627 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70.0 days-84.0 days 2 45.35 % 0.05 0.07 automated blood cell counting method 60634 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait male 70.0 days-84.0 days 1 51.3 fl automated blood cell counting method 60739 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount female 70.0 days-84.0 days 2 5.7 g/dl 0.0 0.0 standard blood chemistry panel 61228 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity male 70.0 days-84.0 days 1 6.9 x 1000 cells/ul automated blood cell counting method 61365 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount female 70.0 days-84.0 days 2 63.0 mg/dl 1.0 1.41 standard blood chemistry panel 62366 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount male 70.0 days-84.0 days 1 31.0 U/l standard blood chemistry panel 61437 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount female 70.0 days-84.0 days 2 23.0 mg/dl 4.0 5.66 standard blood chemistry panel 60152 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount male 70.0 days-84.0 days 1 19.0 mmol/l standard blood chemistry panel 61601 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount male 70.0 days-84.0 days 1 139.0 U/l standard blood chemistry panel 60391 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount male 70.0 days-84.0 days 1 4.1 g/dl standard blood chemistry panel 61897 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70.0 days-84.0 days 2 38.0 cm 0.0 0.0 in vivo ruler method 63658 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass male 70.0 days-84.0 days 2 0.55 g 0.02 0.03 digital scale post excision weight measurement 63730 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass female 70.0 days-84.0 days 2 0.39 g 0.01 0.01 digital scale post excision weight measurement 63737 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass female 70.0 days-84.0 days 2 0.6 g 0.05 0.07 digital scale post excision weight measurement 63347 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass male 70.0 days-84.0 days 2 271.0 g 6.0 8.49 whole body digital scale 63586 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 2 -6.96 null 0.03 0.05 wire myography using a Digi-Med tissue force analysis system with force transducer 62821 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity male 70.0 days-84.0 days 1 1.1 x 1000 cells/ul automated blood cell counting method 60831 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount male 70.0 days-84.0 days 1 2.3 g/dl standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 60913 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70.0 days-84.0 days 2 31.5 g/dl 0.1 0.14 automated blood cell counting method 61146 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 1 3.4 mmol/l flame atomic emission spectrometry 61293 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 2 4.35 mmol/l 0.75 1.06 flame atomic emission spectrometry 61300 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity female 70.0 days-84.0 days 2 5.5 x 1000 cells/ul 0.1 0.14 automated blood cell counting method 61372 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount male 70.0 days-84.0 days 1 99.0 mmol/l standard blood chemistry panel 62287 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity female 70.0 days-84.0 days 2 0.11 x 1000 cells/ul 0.06 0.08 automated blood cell counting method 61680 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 1 144.0 mmol/l flame atomic emission spectrometry 61775 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount male 70.0 days-84.0 days 1 90.0 U/l standard blood chemistry panel 61969 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount male 70.0 days-84.0 days 1 0.1 mg/dl standard blood chemistry panel 62123 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity male 70.0 days-84.0 days 1 0.0 x 1000 cells/ul automated blood cell counting method 62205 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum alanine aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount female 70.0 days-84.0 days 2 43.5 U/l 4.5 6.36 standard blood chemistry panel 61444 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount male 70.0 days-84.0 days 1 6.7 mg/dl standard blood chemistry panel 61529 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount female 70.0 days-84.0 days 2 9.9 mg/dl 0.1 0.14 standard blood chemistry panel 60224 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70.0 days-84.0 days 1 14.3 g/dl automated blood cell counting method 60299 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount female 70.0 days-84.0 days 2 103.5 U/l 4.5 6.36 standard blood chemistry panel 60398 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70.0 days-84.0 days 2 23.5 cm 0.5 0.71 in vivo ruler method 63504 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 2 48.5 % 2.5 3.54 wire myography using a Digi-Med tissue force analysis system with force transducer 62598 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70.0 days-84.0 days 2 0.01 umol/l 0.0 0.0 wire myography using a Digi-Med tissue force analysis system with force transducer 62742 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 2 1.11 E-7mole 0.09 0.13 wire myography using a Digi-Med tissue force analysis system with force transducer 62998 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity female 70.0 days-84.0 days 2 0.56 x 1000 cells/ul 0.07 0.09 automated blood cell counting method 60838 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount female 70.0 days-84.0 days 2 1.95 g/dl 0.05 0.07 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 60920 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount male 70.0 days-84.0 days 1 0.3 mg/dl automated plasma creatinine analysis 60995 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount female 70.0 days-84.0 days 2 0.3 mg/dl 0.1 0.14 automated plasma creatinine analysis 61002 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait male 70.0 days-84.0 days 1 29.0 mmol/l standard blood chemistry panel 61067 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 2 141.5 mmol/l 1.5 2.12 flame atomic emission spectrometry 61782 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity female 70.0 days-84.0 days 2 0.0 x 1000 cells/ul 0.0 0.0 automated blood cell counting method 62212 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount female 70.0 days-84.0 days 2 8.5 mg/dl 0.5 0.71 standard blood chemistry panel 61536 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount female 70.0 days-84.0 days 2 21.0 mmol/l 0.0 0.0 standard blood chemistry panel 61608 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70.0 days-84.0 days 2 14.25 g/dl 0.05 0.07 automated blood cell counting method 60306 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount female 70.0 days-84.0 days 2 3.75 g/dl 0.05 0.07 standard blood chemistry panel 61904 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount female 70.0 days-84.0 days 2 182.5 U/l 52.5 74.25 standard blood chemistry panel 61976 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity male 70.0 days-84.0 days 1 5.52 x 1000 cells/ul automated blood cell counting method 62051 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70.0 days-84.0 days 1 8.44 x 10E6 cells/ul automated blood cell counting method 60545 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass male 70.0 days-84.0 days 2 0.15 g 0.0 0.01 digital scale post excision weight measurement 63268 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70.0 days-84.0 days 2 20.0 cm 0.0 0.0 in vivo ruler method 63511 529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70.0 days-84.0 days 2 -8.15 null 0.09 0.12 wire myography using a Digi-Med tissue force analysis system with force transducer EC50 value is moles/liter 63065 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 1 73.0 % wire myography using a Digi-Med tissue force analysis system with force transducer 62592 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70.0 days-84.0 days 1 0.03 umol/l wire myography using a Digi-Med tissue force analysis system with force transducer 62736 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass male 70.0 days-84.0 days 1 277.0 g whole body digital scale 62902 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 1 1.08 E-7mole wire myography using a Digi-Med tissue force analysis system with force transducer 62992 528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait female 70.0 days-84.0 days 2 25.5 mmol/l 0.5 0.71 standard blood chemistry panel 61074 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70.0 days-84.0 days 1 33.0 g/dl automated blood cell counting method 61139 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount male 70.0 days-84.0 days 1 6.4 g/dl standard blood chemistry panel 61221 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount male 70.0 days-84.0 days 1 79.0 mg/dl standard blood chemistry panel 62359 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount male 70.0 days-84.0 days 1 208.0 mg/dl standard blood chemistry panel 62451 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity male 70.0 days-84.0 days 1 0.28 x 1000 cells/ul automated blood cell counting method 61673 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount female 70.0 days-84.0 days 2 0.2 mg/dl 0.0 0.0 standard blood chemistry panel 62130 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity female 70.0 days-84.0 days 2 4.84 x 1000 cells/ul 0.02 0.03 automated blood cell counting method 62058 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70.0 days-84.0 days 1 16.9 pg automated blood cell counting method 60463 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70.0 days-84.0 days 2 18.0 pg 0.0 0.0 automated blood cell counting method 60470 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70.0 days-84.0 days 2 7.92 x 10E6 cells/ul 0.02 0.02 automated blood cell counting method 60552 527