| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
51.0 days
| 5 |
8.1 |
um |
0.4 |
0.89 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
35 |
days |
pVAX2-rGDNF |
superior hemisphere - photoreceptor IS |
108711 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
70.0 days
| 4 |
8.3 |
um |
1.7 |
3.4 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
54 |
days |
pVAX2-rGDNF |
superior hemisphere |
108744 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
sham gene transfer using an empty plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
51.0 days
| 5 |
6.4 |
um |
0.3 |
0.67 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
35 |
days |
|
superior hemisphere - photoreceptor IS |
108712 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
70.0 days
| 4 |
9.2 |
um |
1.0 |
2.0 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
54 |
days |
|
superior hemisphere |
108743 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
sham gene transfer using an empty plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
70.0 days
| 5 |
0.9 |
um |
0.2 |
0.45 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
54 |
days |
|
superior hemisphere - photoreceptor IS |
108716 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
70.0 days
| 5 |
1.8 |
um |
0.4 |
0.89 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
54 |
days |
pVAX2-rGDNF |
superior hemisphere - photoreceptor IS |
108715 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
87.0 days
| 5 |
1.5 |
um |
0.4 |
0.89 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
71 |
days |
pVAX2-rGDNF |
superior hemisphere - photoreceptor IS |
108723 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
sham gene transfer using an empty plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
87.0 days
| 5 |
1.1 |
um |
0.5 |
1.12 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
71 |
days |
|
superior hemisphere - photoreceptor IS |
108724 |
3131 |
| RCS-p+/LavRrrc |
photoreceptor inner segment thickness |
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
photoreceptor inner segment morphology trait |
both |
70.0 days
| 4 |
5.2 |
um |
1.2 |
2.4 |
ex vivo light microscopy with histochemistry and digital image analysis |
0.0 |
plasmid delivery |
54 |
days |
pVAX2-rGDNF |
superior hemisphere |
108745 |
3131 |