RCS/N |
scotopic A wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
62 days
| 6 |
175.0 |
uV |
14.7 |
36.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
60 |
days |
treated eye |
scotopic a-wave amplitude ERG |
108680 |
3129 |
RCS/N |
scotopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
62 days
| 6 |
500.0 |
uV |
61.24 |
150.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
60 |
days |
treated eye |
scotopic b-wave amplitude ERG |
108682 |
3129 |
RCS/N |
photopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled visible light condition (30 cd/m2) (for 0.1 hours) then visible light stimulus (10 cd x s/m2) and controlled visible light condition (30 cd/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
cone electrophysiology trait |
not specified |
242 days
| 4 |
30.0 |
uV |
5.5 |
11.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
240 |
days |
treated eye |
photopic b-wave amplitude ERG |
108685 |
3129 |
RCS/N |
photopic B wave amplitude of ERG waveform |
lensotomy then controlled visible light exposure (for 0.2 hours) then visible light stimulus (100 cd x s/m2) |
Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. |
cone electrophysiology trait |
not specified |
60 days
| 3 |
13.7 |
uV |
2.19 |
3.8 |
electroretinography |
cornea |
0.0 |
lens puncture |
30 |
days |
|
photopic b-wave ERG |
108569 |
3124 |
RCS/N |
ERG oscillatory potential |
lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) |
Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. |
eye electrophysiology trait |
not specified |
60 days
| 3 |
67.6 |
uV |
16.69 |
28.9 |
electroretinography |
cornea |
0.0 |
lens puncture |
30 |
days |
|
scotopic ocillatory index ERG |
108568 |
3124 |
RCS/N |
scotopic A wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
62 days
| 6 |
16.0 |
uV |
6.94 |
17.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
60 |
days |
contralateral control eye |
scotopic a-wave amplitude ERG |
108681 |
3129 |
RCS/N |
scotopic B wave amplitude of ERG waveform |
gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.01 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
242 days
| 4 |
223.0 |
uV |
28.0 |
56.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
240 |
days |
treated eye |
scotopic b-wave amplitude ERG |
108684 |
3129 |
RCS/N |
scotopic A wave amplitude of ERG waveform |
lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) |
Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. |
rod electrophysiology trait |
not specified |
60 days
| 3 |
18.3 |
uV |
4.79 |
8.3 |
electroretinography |
cornea |
0.0 |
lens puncture |
30 |
days |
|
scotopic a-wave ERG |
108566 |
3124 |
RCS/N |
ERG oscillatory potential |
lensotomy then controlled visible light exposure (for 0.2 hours) then visible light stimulus (100 cd x s/m2) |
Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. |
eye electrophysiology trait |
not specified |
60 days
| 3 |
33.1 |
uV |
2.19 |
3.8 |
electroretinography |
cornea |
0.0 |
lens puncture |
30 |
days |
|
photopic ocillatory index |
108570 |
3124 |
RCS/N |
scotopic B wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) |
Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. |
rod electrophysiology trait |
not specified |
62 days
| 6 |
61.0 |
uV |
19.6 |
48.0 |
electroretinography |
cornea |
0.0 |
AAV8 injection |
60 |
days |
contralateral control eye |
scotopic b-wave amplitude ERG |
108683 |
3129 |
RCS/N |
scotopic B wave amplitude of ERG waveform |
lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) |
Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. |
rod electrophysiology trait |
not specified |
60 days
| 3 |
30.5 |
uV |
7.51 |
13.0 |
electroretinography |
cornea |
0.0 |
lens puncture |
30 |
days |
|
scotopic b-wave ERG |
108567 |
3124 |