abnormal epigenetic regulation of gene expression +
abnormal fibroblast physiology +
abnormal germ cell physiology +
abnormal hepatoblast physiology +
abnormal intestinal crypt stem cell physiology +
any functional anomaly in the cells found in the zone occupying the bottom region of the crypt that provide the source of most of the cell types of the intestinal epithelium, proliferate by mitotic division, and differentiate into columnar or goblet cells
abnormal intestinal epithelial transmembrane transport +