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Ontology Browser

Term:
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (GO:0002486)
Annotations: Rat: (48) Mouse: (44) Human: (20) Chinchilla: (0) Bonobo: (10) Dog: (6) Squirrel: (17) Pig: (20) Naked Mole-rat: (3) Green Monkey: (15)
Parent Terms Term With Siblings Child Terms
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent  
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent  
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.

Synonyms
Exact Synonyms: TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
Definition Sources: GOC:add, PMID:14647477, PMID:15771591

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