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Ontology Browser

Term:
hypoxia-inducible factor-proline dioxygenase activity (GO:0160082)
Annotations: Rat: (3) Mouse: (4) Human: (4) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
hypoxia-inducible factor-proline dioxygenase activity  
Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit].
procollagen-proline 4-dioxygenase activity  

Synonyms
Exact Synonyms: HIF prolyl hydroxylase
Broad Synonyms: HIF hydroxylase
Xrefs: EC:1.14.11.29 ;   RHEA:48400
Definition Sources: PMID:11595184, PMID:11598268

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