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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:kidney papillary necrosis
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Accession:DOID:2981 term browser browse the term
Definition:A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
Synonyms:exact_synonym: necrotizing renal papillitides;   necrotizing renal papillitis;   papillary necrosis;   renal medullary necrosis
 primary_id: MESH:D007681
 xref: EFO:1001004
For additional species annotation, visit the Alliance of Genome Resources.


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  disease 21126
    disease of anatomical entity 18213
      Urogenital Diseases 5221
        urinary system disease 2829
          kidney disease 2585
            kidney papillary necrosis 0
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