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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:cilostazol pharmacodynamics pathway
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Accession:PW:0002288 term browser browse the term
Definition:The pathway of cilostazol-interaction and of the biochemical or physiological responses to drug. The drug is a selective inhibitor of phosphodiesterase type 3. The increase in cyclic AMP (cAMP) and subsequent increase in active protein kinase A (PKA) leads to inhibition of platelet aggregation. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00263

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cilostazol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D ISO SMPDB SMP:00263 NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3924
    drug pathway 348
      blood and blood forming organs drug pathway 49
        antithrombotic drug pathway 49
          antiplatelet drug pathway 27
            cilostazol drug pathway 1
              cilostazol pharmacodynamics pathway 1
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