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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:impaired natural killer cell mediated cytotoxicity
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Accession:MP:0005070 term browser browse the term
Definition:impaired ability of directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors
Synonyms:exact_synonym: defective NK cell cytolysis;   defective natural killer cell cytolysis;   impaired NK cell cytolysis;   impaired NK cell mediated cell death;   impaired NK cell mediated cell killing;   impaired NK cell mediated cytolysis;   impaired NK cell mediated cytotoxicity;   impaired natural killer cell mediated cell death;   impaired natural killer cell mediated cell killing;   impaired natural killer cell mediated cytolysis
 broad_synonym: impaired killer activity


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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal innate immunity 0
          abnormal NK cell physiology 0
            abnormal natural killer cell mediated cytotoxicity 0
              impaired natural killer cell mediated cytotoxicity 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal adaptive immunity 0
          abnormal leukocyte physiology 0
            abnormal lymphocyte physiology 0
              abnormal NK cell physiology 0
                abnormal natural killer cell mediated cytotoxicity 0
                  impaired natural killer cell mediated cytotoxicity 0
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