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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased T follicular helper cell number
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Accession:MP:0010187 term browser browse the term
Definition:reduced number of the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Synonyms:xref: CL:0002038


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Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal leukocyte morphology 0
            abnormal leukocyte cell number 0
              decreased leukocyte cell number 0
                decreased lymphocyte cell number 0
                  decreased T cell number 0
                    decreased T-helper cell number 0
                      decreased T follicular helper cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal leukocyte morphology 0
            abnormal mononuclear cell morphology 0
              abnormal lymphocyte morphology 0
                abnormal T cell morphology 0
                  abnormal effector T cell morphology 0
                    abnormal CD4-positive, alpha beta T cell morphology 0
                      abnormal CD4-positive helper T cell morphology 0
                        abnormal T follicular helper cell morphology 0
                          abnormal T follicular helper cell number 0
                            decreased T follicular helper cell number 0
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