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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Isothenuria
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Accession:HP:0030036 term browser browse the term
Definition:Inability of the kidneys to produce either concentrated or dilute urine.
Comment:Isothenuria is seen in the final stages of renal failure. It reflects rapid flushing of fluid through the tubules in renal failure as the number of functioning nephrons decreases; the normal concentrating (particularly) and diluting mechanisms of the kidney do not have time to function. The consequence is that the specific gravity of the urine becomes approximately the same as that of the glomerular filtrate.
Synonyms:xref: UMLS:C4022665


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Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the genitourinary system 0
        Abnormality of the urinary system 0
          Abnormality of the urinary system physiology 0
            Abnormal renal physiology 0
              Isothenuria 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the genitourinary system 0
        Abnormality of the urinary system 0
          Abnormality of the upper urinary tract 0
            Abnormality of the kidney 0
              Abnormal renal physiology 0
                Isothenuria 0
paths to the root