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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Functional abnormality of the middle ear
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Accession:HP:0011452 term browser browse the term
Definition:An abnormality of the function of the middle ear.
Comment:The middle ear comprises the tympanic cavity in the temporal bone of the skull behind the eardrum, and is separated from the outer ear by the ear drum. The tympanic cavity contains the auditory ossicles (malleus, incus, stapes) that vibrate when exposed to sound, forming a chain that extends to the oval window of the inner ear and whose main function is to amplify sound. Additionally, the middle ear connects to the back of the throat and nose through the Eustachian tube.
Synonyms:xref: UMLS:C4021846

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Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the ear 0
        Abnormal ear morphology 0
          Abnormality of the middle ear 0
            Functional abnormality of the middle ear 0
              Abnormal middle ear reflexes + 0
              Conductive hearing impairment + 0
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