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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Acanthosis nigricans
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Accession:HP:0000956 term browser browse the term
Definition:A dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck.
Comment:Acanthosis nigricans is seen in a variety of syndromes including those characterized by insulin resistance or fibroblast growth factor receptor (FGFR) mutations, and may also occur as an adverse effect of several medications that promote hyperinsulinemia.
Synonyms:exact_synonym: Darkened and thickened skin;   Keratosis nigricans
 alt_id: HP:0007498;   HP:0007518;   HP:0007591
 xref: EFO:1000660;   SNOMEDCT_US:402599005;   SNOMEDCT_US:72129000;   UMLS:C0000889


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the integument 0
        Abnormality of the skin 0
          Abnormal skin morphology 0
            Thickened skin 0
              Epidermal thickening 0
                Acanthosis nigricans 0
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