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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Generalized tonic seizure
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Accession:HP:0010818 term browser browse the term
Definition:A generalized tonic seizure is a type of generalized motor seizure characterized by bilateral limb stiffening or elevation, often with neck stiffening without a subsequent clonic phase. The tonic activity can be a sustained abnormal posture, either in extension or flexion, sometimes accompanied by tremor of the extremities.
Comment:Characterized by a sudden increase in muscle tone whereby the body, arms, or legs make sudden stiffening movements and consciousness is usually preserved. Tonic seizures can occur during sleep. Tonic seizures usually affect both sides of the body, and cause a fall if the affected person was standing when the seizure started.
Synonyms:exact_synonym: Generalised hypertonic seizure;   Generalised tonic seizure;   Generalised tonic seizures;   Generalized hypertonic seizure;   Generalized tonic seizures
 related_synonym: Hypertonic seizures
 alt_id: HP:0002184
 xref: UMLS:C1836508


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system physiology 0
          Seizure 0
            Generalized-onset seizure 0
              Generalized-onset motor seizure 0
                Generalized tonic seizure 0
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