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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of response to DNA damage stimulus
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Accession:GO:2001022 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.
Synonyms:exact_synonym: positive regulation of DNA damage response;   positive regulation of cellular DNA damage response;   positive regulation of cellular response to DNA damage stimulus;   positive regulation of response to genotoxic stress

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positive regulation of response to DNA damage stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 involved_in ISO (PMID:22399800) RGD PMID:22399800 NCBI chr16:19,799,943...19,826,057
Ensembl chr16:19,800,463...19,803,796 		JBrowse link
G Atm ATM serine/threonine kinase IMP RGD PMID:28007901 RGD:12879399 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624 		JBrowse link
G Fmr1 FMRP translational regulator 1 involved_in IBA
ISO
ISS
IEA		 PMID:21873635
(MGI:5602914|PMID:24813610)
(PMID:24813610)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:24813610, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5602914, RGD:13792537 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314 		JBrowse link
G Fxr1 FMR1 autosomal homolog 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:120,529,716...120,570,356
Ensembl chr 2:120,512,899...120,570,355 		JBrowse link
G Fxr2 FMR1 autosomal homolog 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:56,237,814...56,257,877
Ensembl chr10:56,237,755...56,257,890 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS		 (PMID:16061642), (PMID:19465398)
GO_REF:0000024		 RGD
UniProt		 PMID:16061642 PMID:19465398 GO_REF:0000024 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS		 (PMID:19179467)
GO_REF:0000024		 RGD
UniProt		 PMID:19179467 GO_REF:0000024 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20395202)		 UniProt
RGD		 PMID:20395202 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421 		JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component involved_in ISO
IEA
ISS		 (PMID:18086888)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18086888 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:196,857,490...196,883,907
Ensembl chr 1:196,857,461...196,884,302 		JBrowse link
G Nsmce4a NSE4 homolog A, SMC5-SMC6 complex component involved_in ISO (PMID:18086888) RGD PMID:18086888 NCBI chr 1:201,103,750...201,110,838
Ensembl chr 1:201,096,059...201,110,928 		JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (MGI:3844416|PMID:19124460) RGD PMID:19124460 MGI:3844416 NCBI chr 1:198,448,790...198,451,078
Ensembl chr 1:198,449,040...198,450,688 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:3844416|PMID:19124460) RGD PMID:19124460 MGI:3844416 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:17938203)
GO_REF:0000107		 RGD
Ensembl		 PMID:17938203 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746 		JBrowse link
positive regulation of base-excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam168a family with sequence similarity 168, member A involved_in ISO
IBA		 (PMID:25260657)
PMID:21873635		 RGD PMID:25260657, PMID:21873635 RGD:13792537 NCBI chr 1:165,723,278...165,880,612
Ensembl chr 1:165,724,451...165,878,652 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:18973764) RGD PMID:18973764 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167 		JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:51,818,887...51,834,443
Ensembl chr15:51,818,897...51,834,030 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (PMID:20599664) RGD PMID:20599664 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:9733515) RGD PMID:9733515 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:9925639) RGD PMID:9925639 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9529249) RGD PMID:9529249 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,785,017...26,795,723
Ensembl chr17:26,785,029...26,797,161 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (MGI:5297787|PMID:16269335) RGD PMID:16269335 MGI:5297787 NCBI chr10:62,007,150...62,010,774
Ensembl chr10:62,007,150...62,009,582 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19197340)		 UniProt
RGD		 PMID:19197340 GO_REF:0000024 NCBI chr 3:46,488,963...46,621,873
Ensembl chr 3:46,488,186...46,621,873 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)		 RGD PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5318016|PMID:20736167)		 RGD PMID:20736167, PMID:21873635 MGI:5318016, RGD:13792537 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5318016|PMID:20736167)		 RGD PMID:20736167, PMID:21873635 MGI:5318016, RGD:13792537 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:88,101,213...88,112,719
Ensembl chr 1:88,103,719...88,112,683 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) RGD PMID:16213212 NCBI chr10:55,492,417...55,495,547
Ensembl chr10:55,492,404...55,496,012 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:144,939,616...144,966,364
Ensembl chr 7:144,939,619...144,966,370 		JBrowse link
positive regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISO
ISS
IEA		 (PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 involved_in IMP
ISO		 PMID:19282473
(MGI:3698695|PMID:17121854)		 RGD PMID:17121854, PMID:19282473 MGI:3698695, RGD:8553580 NCBI chr 1:170,387,625...170,411,263
Ensembl chr 1:170,387,609...170,404,056 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19261746), (PMID:19261748), (PMID:19261749)		 UniProt
RGD		 PMID:19261746 PMID:19261748 PMID:19261749 GO_REF:0000024 NCBI chr16:19,792,720...19,798,886
Ensembl chr16:19,792,838...19,798,894 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO
ISS		 (PMID:19261748)
GO_REF:0000024		 RGD
UniProt		 PMID:19261748 GO_REF:0000024 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA		 (PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000107		 RGD
Ensembl		 PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000107 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 involved_in ISO
ISS		 (PMID:17525341), (PMID:19261746), (PMID:19261748)
GO_REF:0000024		 RGD
UniProt		 PMID:17525341 PMID:19261746 PMID:19261748 GO_REF:0000024 NCBI chr 9:9,863,380...9,865,920
Ensembl chr 9:9,863,404...9,865,920 		JBrowse link
G Cbx8 chromobox 8 IMP RGD PMID:23572236 RGD:9586727 NCBI chr10:108,148,073...108,150,511
Ensembl chr10:108,148,073...108,150,511 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma involved_in ISS
ISO		 PMID:16255782
(PMID:16255782)		 RGD PMID:16255782, PMID:16255782 RGD:8554294 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656 		JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:24049074) RGD PMID:24049074 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:17115032) RGD PMID:17115032 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO UniProtKB:Q03468 (PMID:22483866)
UniProtKB:P0DP91 (PMID:22483866)		 RGD PMID:22483866 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in IBA
ISO		 PMID:21873635
(PMID:7664335)		 RGD PMID:7664335, PMID:21873635 RGD:13792537 NCBI chr 2:39,434,617...39,473,392
Ensembl chr 2:39,434,634...39,472,017 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO
IBA		 (PMID:19234442)
PMID:21873635		 RGD PMID:19234442, PMID:21873635 RGD:13792537 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:162,285,275...162,470,642
Ensembl chr 3:162,346,490...162,470,065 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:19234442)		 RGD PMID:19234442, PMID:21873635 RGD:13792537 NCBI chr 5:150,833,754...150,915,390
Ensembl chr 5:150,787,043...150,913,757 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:23,237,617...23,611,580
Ensembl chr 1:23,409,408...23,610,164 		JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:14975937) RGD PMID:14975937 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase IDA RGD PMID:1945835 RGD:729332 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190 		JBrowse link
G Npas2 neuronal PAS domain protein 2 involved_in ISO (PMID:18819933) RGD PMID:18819933 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase IMP RGD PMID:15158362 RGD:2316739 NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISS
ISO		 GO_REF:0000024
(PMID:24939902)		 UniProt
RGD		 PMID:24939902 GO_REF:0000024 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Rnf168 ring finger protein 168 involved_in IEA
ISS
ISO		 GO_REF:0000104
GO_REF:0000024
(PMID:19203578), (PMID:19203579), (PMID:23760478)		 UniProt
RGD		 PMID:19203578 PMID:19203579 PMID:23760478 GO_REF:0000024 GO_REF:0000104 NCBI chr11:71,721,242...71,743,421
Ensembl chr11:71,721,250...71,743,421 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO
IEA
ISS		 (PMID:18001824), (PMID:18001825)
GO_REF:0000104
GO_REF:0000024		 RGD
UniProt		 PMID:18001824 PMID:18001825 GO_REF:0000024 GO_REF:0000104 NCBI chr20:8,285,380...8,309,858
Ensembl chr20:8,285,296...8,309,908 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:23911537) RGD PMID:23911537 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:19934257)
GO_REF:0000107		 RGD
Ensembl		 PMID:19934257 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:24790221) RGD PMID:24790221 NCBI chr 9:119,675,750...119,818,620
Ensembl chr 9:119,676,628...119,818,310 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO
IBA		 (PMID:25928429)
PMID:21873635		 RGD PMID:25928429, PMID:21873635 RGD:13792537 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063 		JBrowse link
G Tmem161a transmembrane protein 161A involved_in ISO (PMID:16551573) RGD PMID:16551573 NCBI chr16:20,985,841...20,996,351
Ensembl chr16:20,986,687...20,994,379 		JBrowse link
G Trim28 tripartite motif-containing 28 involved_in ISO (PMID:17178852) RGD PMID:17178852 NCBI chr 1:65,544,369...65,551,043
Ensembl chr 1:65,544,373...65,551,043 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N involved_in ISO (PMID:16129784) RGD PMID:16129784 NCBI chr 7:36,610,147...36,640,190
Ensembl chr 7:36,610,147...36,640,189 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 IMP RGD PMID:12750002 RGD:1299567 NCBI chr11:89,557,273...89,591,175
Ensembl chr11:89,557,273...89,591,175 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748)		 UniProt
Ensembl
RGD		 PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr17:10,061,915...10,130,921
Ensembl chr17:10,065,947...10,130,907 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISO
ISS		 (PMID:25512560)
GO_REF:0000024		 RGD
UniProt		 PMID:25512560 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857 		JBrowse link
positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:23797032) RGD PMID:23797032 NCBI chr 9:114,113,642...114,133,908
Ensembl chr 9:114,111,580...114,132,492 		JBrowse link
G Fmn2 formin 2 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)		 RGD
Ensembl		 PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISS
ISO		 GO_REF:0000024
(MGI:6467697|PMID:29125140), (MGI:6716977|PMID:33115731)		 UniProt
RGD		 PMID:29125140 PMID:33115731 GO_REF:0000024 MGI:6467697 MGI:6716977 NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592 		JBrowse link
G LOC100910636 zinc finger CW-type PWWP domain protein 1-like involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) RGD PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr12:21,690,074...21,720,186
Ensembl chr12:21,689,095...21,720,094 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase involved_in ISO (PMID:24147153) RGD PMID:24147153 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190 		JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) RGD PMID:29125140 MGI:6467697 NCBI chr 8:85,719,447...85,720,806
Ensembl chr 8:85,719,496...85,720,790 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 involved_in ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:4,095,126...4,195,819
Ensembl chr 2:4,095,129...4,195,810 		JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 involved_in IBA
ISO		 PMID:21873635
(PMID:25931565)		 RGD PMID:25931565, PMID:21873635 RGD:13792537 NCBI chr 1:264,670,836...264,733,465
Ensembl chr 1:264,670,841...264,733,306 		JBrowse link
G Spidr scaffold protein involved in DNA repair involved_in ISO (PMID:23509288) RGD PMID:23509288 NCBI chr11:89,009,931...89,260,361
Ensembl chr11:89,009,931...89,260,297 		JBrowse link
G Spire1 spire-type actin nucleation factor 1 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr18:63,226,557...63,357,420
Ensembl chr18:63,226,557...63,357,298 		JBrowse link
G Spire2 spire-type actin nucleation factor 2 involved_in ISO (PMID:26287480) RGD PMID:26287480 NCBI chr19:56,136,904...56,175,500
Ensembl chr19:56,136,904...56,175,500 		JBrowse link
G Timeless timeless circadian regulator involved_in ISO
ISS		 (PMID:23797032)
GO_REF:0000024		 RGD
UniProt		 PMID:23797032 GO_REF:0000024 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27715493)		 UniProt
RGD		 PMID:27715493 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857 		JBrowse link
G Zcwpw1 zinc finger CW-type and PWWP domain containing 1 involved_in ISO (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261), (MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) RGD PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506 MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709 NCBI chr12:21,418,874...21,450,617
Ensembl chr12:21,950,993...21,973,474 		JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 involved_in ISO
ISS		 (PMID:29925947)
GO_REF:0000024		 RGD
UniProt		 PMID:29925947 GO_REF:0000024 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649 		JBrowse link
G Arid2 AT-rich interaction domain 2 involved_in ISO (PMID:28381560) RGD PMID:28381560 NCBI chr 7:137,680,564...137,798,329
Ensembl chr 7:137,680,530...137,795,655 		JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:2448558 (MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:5648586 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G Fancb FA complementation group B involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1328362 (MGI:5648586|PMID:25520194)		 RGD PMID:25520194, PMID:21873635 MGI:5648586, RGD:13792537 NCBI chr  X:31,124,018...31,140,790
Ensembl chr  X:31,124,018...31,140,711 		JBrowse link
G Fus FUS RNA binding protein involved_in ISO (PMID:10567410) RGD PMID:10567410 NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member involved_in ISO
ISS		 (PMID:31609975)
(MGI:6716962|PMID:25936915)
GO_REF:0000024		 RGD
UniProt		 PMID:25936915 PMID:31609975 GO_REF:0000024 MGI:6716962 NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592 		JBrowse link
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component involved_in ISO (PMID:29225034) RGD PMID:29225034 NCBI chr 1:261,191,646...261,229,070
Ensembl chr 1:261,191,646...261,229,046 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:35,680,687...35,704,685
Ensembl chr10:35,680,658...35,704,776 		JBrowse link
G Ooep oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) RGD PMID:29955025 MGI:6272426 NCBI chr 8:85,719,447...85,720,806
Ensembl chr 8:85,719,496...85,720,790 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000024		 RGD
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 involved_in ISO (PMID:17996710), (PMID:17996711) RGD PMID:17996710 PMID:17996711 NCBI chr 4:159,469,803...159,482,869
Ensembl chr 4:159,469,804...159,482,869 		JBrowse link
G Timeless timeless circadian regulator involved_in ISO
ISS		 (PMID:26344098), (PMID:30356214)
GO_REF:0000024		 RGD
UniProt		 PMID:26344098 PMID:30356214 GO_REF:0000024 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO (PMID:29925947) RGD PMID:29925947 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105 		JBrowse link
G Wdr48 WD repeat domain 48 involved_in ISO (PMID:27239033), (PMID:27463890) RGD PMID:27239033 PMID:27463890 NCBI chr 8:128,577,080...128,610,287
Ensembl chr 8:128,577,080...128,610,287 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISO
ISS		 (PMID:25512560)
GO_REF:0000024		 RGD
UniProt		 PMID:25512560 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857 		JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622 		JBrowse link
G Fh fumarate hydratase involved_in ISO
ISS		 (PMID:26237645)
GO_REF:0000024		 RGD
UniProt		 PMID:26237645 GO_REF:0000024 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377 		JBrowse link
G Kdm4d lysine demethylase 4D acts_upstream_of_or_within ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:12,968,192...12,993,651
Ensembl chr 8:13,511,805...13,513,337 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO		 GO_REF:0000024
(PMID:28114273)		 UniProt
RGD		 PMID:28114273 GO_REF:0000024 NCBI chr 1:219,000,844...219,050,211
Ensembl chr 1:219,000,844...219,050,211 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO
ISS		 (PMID:28114273)
GO_REF:0000024		 RGD
UniProt		 PMID:28114273 GO_REF:0000024 NCBI chr 1:72,666,662...72,674,271
Ensembl chr 1:72,666,665...72,674,271 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255 		JBrowse link
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (PMID:24598253) RGD PMID:24598253 NCBI chr 8:115,173,440...115,179,543
Ensembl chr 8:115,173,453...115,179,191 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:12032095) RGD PMID:12032095 NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:26237645) RGD PMID:26237645 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:28241136)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)		 RGD PMID:23306437 PMID:23333305 PMID:28241136 MGI:5468037 MGI:5476381 NCBI chr 3:37,599,540...37,648,818
Ensembl chr 3:37,599,728...37,647,631 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:20620605), (PMID:21491884) RGD PMID:20620605 PMID:21491884 NCBI chr 4:140,092,346...140,104,495
Ensembl chr 4:140,092,352...140,105,316 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in IBA
ISO		 PMID:21873635
(PMID:29656893)		 RGD PMID:29656893, PMID:21873635 RGD:13792537 NCBI chr 3:125,318,682...125,396,705
Ensembl chr 3:125,320,680...125,396,821 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893), (PMID:29789392) RGD PMID:29656893 PMID:29789392 NCBI chr16:10,570,307...10,661,528
Ensembl chr16:10,570,314...10,661,528 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:119,675,750...119,818,620
Ensembl chr 9:119,676,628...119,818,310 		JBrowse link
G Top2b DNA topoisomerase II beta IMP RGD PMID:22019940 RGD:13432143 NCBI chr15:10,262,972...10,319,741
Ensembl chr15:10,262,651...10,320,233 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25512560)		 UniProt
RGD		 PMID:25512560 GO_REF:0000024 NCBI chr10:56,169,024...56,185,800
Ensembl chr10:56,169,025...56,185,857 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:70,399,093...70,437,151
Ensembl chr17:70,399,049...70,437,144 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006 		JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22926524)		 Ensembl
RGD		 PMID:22926524 GO_REF:0000107 NCBI chr 3:3,508,084...3,574,787
Ensembl chr 3:3,510,041...3,574,787 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (MGI:5009403|PMID:16816390) RGD PMID:16816390 MGI:5009403 NCBI chr 7:11,414,565...11,428,090
Ensembl chr 7:11,414,446...11,428,552 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5284813|PMID:12509439)		 Ensembl
RGD		 PMID:12509439 GO_REF:0000107 MGI:5284813 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO MGI:2442925 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO MGI:2387096 (MGI:1858539|PMID:10811619) RGD PMID:10811619 MGI:1858539 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)		 RGD PMID:16213212 MGI:5882892 NCBI chr10:55,492,417...55,495,547
Ensembl chr10:55,492,404...55,496,012 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (MGI:4367682|PMID:18617898) RGD PMID:18617898 MGI:4367682 NCBI chr13:36,257,220...36,274,144
Ensembl chr13:36,257,112...36,290,531 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO MGI:2442925|MGI:98834 (MGI:3584078|PMID:15983387) RGD PMID:15983387 MGI:3584078 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354 		JBrowse link
positive regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26221039)		 UniProt
RGD		 PMID:26221039 GO_REF:0000024 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15014079) RGD PMID:15014079 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISO (PMID:15808853) RGD PMID:15808853 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:15342622) RGD PMID:15342622 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369 		JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO UniProtKB:P18887 (PMID:28002403)
UniProtKB:Q60596 (MGI:5902647|PMID:28002403)		 RGD PMID:28002403 MGI:5902647 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO UniProtKB:P09874 (PMID:28002403)
UniProtKB:P11103 (MGI:5902647|PMID:28002403)		 RGD PMID:28002403 MGI:5902647 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      positive regulation of cellular process 6069
        positive regulation of response to DNA damage stimulus 116
          positive regulation of DNA damage checkpoint + 2
          positive regulation of DNA damage response, signal transduction by p53 class mediator + 14
          positive regulation of DNA repair + 78
          positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 11
          positive regulation of telomere maintenance in response to DNA damage + 0
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of response to stimulus 3979
          regulation of response to stress 1308
            regulation of cellular response to stress 683
              regulation of response to DNA damage stimulus 226
                positive regulation of response to DNA damage stimulus 116
                  positive regulation of DNA damage checkpoint + 2
                  positive regulation of DNA damage response, signal transduction by p53 class mediator + 14
                  positive regulation of DNA repair + 78
                  positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 11
                  positive regulation of telomere maintenance in response to DNA damage + 0
paths to the root