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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of response to DNA damage stimulus
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Accession:GO:2001022 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.
Synonyms:exact_synonym: positive regulation of DNA damage response;   positive regulation of cellular DNA damage response;   positive regulation of cellular response to DNA damage stimulus;   positive regulation of response to genotoxic stress


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positive regulation of response to DNA damage stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankle1 ankyrin repeat and LEM domain containing 1 JBrowse link 16 19,799,943 19,826,057 RGD:1624291
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:12879399
G Bclaf1 BCL2-associated transcription factor 1 JBrowse link 1 15,799,753 15,828,838 RGD:1624291
G Eid3 EP300 interacting inhibitor of differentiation 3 JBrowse link 7 26,976,154 26,977,479 RGD:13792537
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
RGD:13792537
RGD:1624291
G Fxr1 FMR1 autosomal homolog 1 JBrowse link 2 120,529,716 120,570,356 RGD:13792537
G Fxr2 FMR1 autosomal homolog 2 JBrowse link 10 56,237,814 56,257,877 RGD:13792537
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1600115
RGD:1624291
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component JBrowse link 1 196,857,490 196,883,907 RGD:1600115
RGD:1624291
G Nsmce4a NSE4 homolog A, SMC5-SMC6 complex component JBrowse link 1 201,103,750 201,110,838 RGD:1624291
RGD:13792537
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
positive regulation of base-excision repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam168a family with sequence similarity 168, member A JBrowse link 1 165,723,278 165,880,612 RGD:1624291
RGD:13792537
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
positive regulation of DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccar2 cell cycle and apoptosis regulator 2 JBrowse link 15 51,818,887 51,834,443 RGD:1624291
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd1 ankyrin repeat domain 1 JBrowse link 1 254,726,985 254,745,673 RGD:1624291
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:1624291
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 JBrowse link 17 26,785,017 26,795,723 RGD:1624291
G Hic1 HIC ZBTB transcriptional repressor 1 JBrowse link 10 62,007,150 62,010,774 RGD:1624291
G Pla2r1 phospholipase A2 receptor 1 JBrowse link 3 46,488,963 46,621,873 RGD:1624291
RGD:1600115
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
G Spred1 sprouty-related, EVH1 domain containing 1 JBrowse link 3 108,795,337 108,861,650 RGD:1624291
RGD:13792537
G Spred2 sprouty-related, EVH1 domain containing 2 JBrowse link 14 104,268,362 104,290,206 RGD:1624291
RGD:13792537
RGD:1600115
G Spred3 sprouty-related, EVH1 domain containing 3 JBrowse link 1 88,101,213 88,112,719 RGD:13792537
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpl26 ribosomal protein L26 JBrowse link 10 55,492,417 55,495,547 RGD:1624291
G Zfp385a zinc finger protein 385A JBrowse link 7 144,939,616 144,966,364 RGD:1624291
positive regulation of DNA repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:1600115
RGD:1624291
G Apbb1 amyloid beta precursor protein binding family B member 1 JBrowse link 1 170,387,625 170,411,263 RGD:8553580
RGD:1624291
G Babam1 BRISC and BRCA1 A complex member 1 JBrowse link 16 19,792,720 19,798,886 RGD:1600115
RGD:1624291
G Babam2 BRISC and BRCA1 A complex member 2 JBrowse link 6 25,666,654 26,135,888 RGD:1624291
RGD:1600115
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1600115
RGD:1624291
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 JBrowse link 9 9,863,380 9,865,920 RGD:1600115
RGD:1624291
G Cbx8 chromobox 8 JBrowse link 10 108,148,073 108,150,511 RGD:9586727
G Cebpg CCAAT/enhancer binding protein gamma JBrowse link 1 91,286,956 91,297,459 RGD:1624291
RGD:8554294
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1624291
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit JBrowse link 2 39,434,617 39,473,392 RGD:1624291
RGD:13792537
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
RGD:13792537
G Eya2 EYA transcriptional coactivator and phosphatase 2 JBrowse link 3 162,285,275 162,470,642 RGD:13792537
G Eya3 EYA transcriptional coactivator and phosphatase 3 JBrowse link 5 150,833,754 150,915,390 RGD:1624291
RGD:13792537
G Eya4 EYA transcriptional coactivator and phosphatase 4 JBrowse link 1 23,237,617 23,611,580 RGD:13792537
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:729332
G Npas2 neuronal PAS domain protein 2 JBrowse link 9 45,901,262 46,081,880 RGD:1624291
G Parg poly (ADP-ribose) glycohydrolase JBrowse link 16 8,350,168 8,457,999 RGD:2316739
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:1624291
RGD:1600115
G Rnf168 ring finger protein 168 JBrowse link 11 71,721,242 71,743,421 RGD:1600115
RGD:1624291
G Rnf8 ring finger protein 8 JBrowse link 20 8,285,380 8,309,858 RGD:1600115
RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
RGD:1600115
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:1624291
G Tigar TP53 induced glycolysis regulatory phosphatase JBrowse link 4 159,635,145 159,654,108 RGD:1624291
RGD:13792537
G Tmem161a transmembrane protein 161A JBrowse link 16 20,985,841 20,996,351 RGD:1624291
G Trim28 tripartite motif-containing 28 JBrowse link 1 65,544,369 65,551,043 RGD:1624291
G Ube2n ubiquitin-conjugating enzyme E2N JBrowse link 7 36,610,147 36,640,190 RGD:1624291
G Ube2v2 ubiquitin conjugating enzyme E2 V2 JBrowse link 11 89,557,273 89,591,175 RGD:1299567
G Uimc1 ubiquitin interaction motif containing 1 JBrowse link 17 10,061,915 10,130,921 RGD:1600115
RGD:13792537
RGD:1624291
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291
positive regulation of DNA repair by transcription from RNA polymerase II promoter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gtf2i general transcription factor II I JBrowse link 12 25,410,804 25,487,970 RGD:1624291
G Prrx1 paired related homeobox 1 JBrowse link 13 81,147,038 81,215,559 RGD:1624291
positive regulation of double-strand break repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx11 DEAD/H-box helicase 11 JBrowse link 9 114,113,642 114,133,908 RGD:1624291
G Fmn2 formin 2 JBrowse link 13 92,569,256 92,887,302 RGD:1624291
G Foxm1 forkhead box M1 JBrowse link 4 161,685,236 161,697,633 RGD:1600115
RGD:13792537
RGD:1624291
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:1624291
G Nudt16 nudix hydrolase 16 JBrowse link 8 113,673,069 113,675,124 RGD:1624291
G Slf1 SMC5-SMC6 complex localization factor 1 JBrowse link 2 4,095,126 4,195,819 RGD:1624291
G Slf2 SMC5-SMC6 complex localization factor 2 JBrowse link 1 264,670,836 264,733,465 RGD:1624291
G Spidr scaffold protein involved in DNA repair JBrowse link 11 89,009,931 89,260,361 RGD:1624291
G Spire1 spire-type actin nucleation factor 1 JBrowse link 18 63,226,557 63,357,420 RGD:1624291
G Spire2 spire-type actin nucleation factor 2 JBrowse link 19 56,136,904 56,175,500 RGD:1624291
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:1624291
RGD:1600115
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr2 actin related protein 2 JBrowse link 14 104,338,486 104,375,840 RGD:1600115
RGD:1624291
G Arid2 AT-rich interaction domain 2 JBrowse link 7 137,680,564 137,798,329 RGD:1624291
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1624291
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fus FUS RNA binding protein JBrowse link 1 199,412,805 199,426,705 RGD:1624291
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 1 261,191,646 261,229,070 RGD:1624291
G Mrnip MRN complex interacting protein JBrowse link 10 35,680,687 35,704,685 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1600115
RGD:1624291
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:1600115
RGD:1624291
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:1624291
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtx3l deltex E3 ubiquitin ligase 3L JBrowse link 11
11
67,758,093
67,768,542
67,767,623
67,772,428
RGD:1624291
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:1600115
RGD:1624291
G Kdm4d lysine demethylase 4D JBrowse link 8 12,968,192 12,993,651 RGD:1624291
G Kmt5b lysine methyltransferase 5B JBrowse link 1 219,000,844 219,050,211 RGD:1624291
RGD:1600115
G Kmt5c lysine methyltransferase 5C JBrowse link 1 72,666,662 72,674,271 RGD:1624291
RGD:1600115
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
G Parp9 poly (ADP-ribose) polymerase family, member 9 JBrowse link 11 67,724,071 67,758,027 RGD:1624291
G Pnkp polynucleotide kinase 3'-phosphatase JBrowse link 1 100,853,475 100,859,202 RGD:1624291
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Setmar SET domain and mariner transposase fusion gene JBrowse link 4 140,092,346 140,104,495 RGD:1624291
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:1624291
G Top2b DNA topoisomerase II beta JBrowse link 15 10,262,972 10,319,741 RGD:13432143
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Mtch2 mitochondrial carrier 2 JBrowse link 3 79,678,141 79,695,356 RGD:1624291
G Nacc2 NACC family member 2 JBrowse link 3 3,508,084 3,574,787 RGD:1624291
RGD:1600115
G Pias4 protein inhibitor of activated STAT, 4 JBrowse link 7 11,414,565 11,428,090 RGD:1624291
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:1624291
RGD:1600115
G Rad9a RAD9 checkpoint clamp component A JBrowse link 1 219,443,347 219,450,574 RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Skil SKI-like proto-oncogene JBrowse link 2 115,862,932 115,891,304 RGD:1624291
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpl26 ribosomal protein L26 JBrowse link 10 55,492,417 55,495,547 RGD:1624291
G Steap3 STEAP3 metalloreductase JBrowse link 13 36,257,220 36,274,144 RGD:1624291
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1624291
positive regulation of mismatch repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:1600115
RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Prkcg protein kinase C, gamma JBrowse link 1 64,407,098 64,433,698 RGD:1624291
positive regulation of single strand break repair term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      positive regulation of cellular process 6118
        positive regulation of response to DNA damage stimulus 112
          positive regulation of DNA damage checkpoint + 1
          positive regulation of DNA damage response, signal transduction by p53 class mediator + 14
          positive regulation of DNA repair + 74
          positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 11
          positive regulation of telomere maintenance in response to DNA damage + 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of response to stimulus 4066
          regulation of response to stress 1394
            regulation of cellular response to stress 724
              regulation of response to DNA damage stimulus 225
                positive regulation of response to DNA damage stimulus 112
                  positive regulation of DNA damage checkpoint + 1
                  positive regulation of DNA damage response, signal transduction by p53 class mediator + 14
                  positive regulation of DNA repair + 74
                  positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage + 11
                  positive regulation of telomere maintenance in response to DNA damage + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.