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ONTOLOGY REPORT - ANNOTATIONS

Term:ciliary basal body-plasma membrane docking
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Accession:GO:0097711 term browser browse the term
Definition:The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
Comment:Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.
Synonyms:exact_synonym: ciliary basal body docking
 related_synonym: anchoring of the basal body to the plasma membrane
 xref: Reactome:R-HSA-5620912 "Anchoring of the basal body to the plasma membrane"


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ciliary basal body-plasma membrane docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEP290 centrosomal protein 290 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:27002738) GO_Central
MGI		 PMID:27002738 GO_REF:0000033 NCBI chr12:88,049,016...88,142,088
Ensembl chr12:88,049,016...88,142,099 		JBrowse link
G RAB3IP RAB3A interacting protein involved_in TAS Reactome Reactome:R-HSA-5620912 NCBI chr12:69,738,242...69,823,204
Ensembl chr12:69,738,860...69,823,204 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20497
    cellular process 19744
      membrane docking 99
        organelle localization by membrane tethering 88
          ciliary basal body-plasma membrane docking 2
Path 2
Term Annotations click to browse term
  biological_process 20497
    cellular process 19744
      cellular component organization or biogenesis 7911
        cellular component organization 7680
          cellular component assembly 3753
            cell projection assembly 697
              plasma membrane bounded cell projection assembly 682
                cilium assembly 455
                  ciliary basal body-plasma membrane docking 2
paths to the root