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ONTOLOGY REPORT - ANNOTATIONS

Term:PAS complex
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Accession:GO:0070772 term browser browse the term
Definition:A phosphatidylinositol kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKFYVE in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.
Synonyms:related_synonym: autophagy-specific phosphatidylinositol 3-kinase complex


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PAS complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vac14 VAC14 component of PIKFYVE complex part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:38,590,569...38,691,911
Ensembl chr19:38,590,569...38,691,909 		JBrowse link
Term paths to the root
Path 1
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  cellular_component 20833
    protein-containing complex 6558
      membrane protein complex 1410
        PAS complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      organelle 13975
        intracellular organelle 13569
          intracellular membrane-bounded organelle 12009
            vacuole 661
              vacuolar membrane 340
                PAS complex 1
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