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ONTOLOGY REPORT - ANNOTATIONS

Term:carnosine synthase activity
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Accession:GO:0047730 term browser browse the term
Definition:Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine.
Synonyms:related_synonym: L-histidine:beta-alanine ligase (AMP-forming);   carnosine synthetase activity;   carnosine-anserine synthetase activity;   carnosine-homocarnosine synthetase activity
 xref: EC:6.3.2.11;   MetaCyc:CARNOSINE-SYNTHASE-RXN;   RHEA:19297;   reactome:R-HSA-6786245 "CARNS1 transforms ATP, L-His, b-Ala to CARN"


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carnosine synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carns1 carnosine synthase 1 enables ISO
IBA		 (PMID:20097752), (PMID:24891507)
GO_REF:0000033		 RGD
GO_Central		 PMID:20097752 PMID:24891507 GO_REF:0000033 NCBI chr 1:201,459,061...201,470,019
Ensembl chr 1:201,459,076...201,469,845 		JBrowse link
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  molecular_function 20626
    catalytic activity 6028
      ligase activity 178
        ligase activity, forming carbon-nitrogen bonds 51
          acid-amino acid ligase activity 24
            carnosine synthase activity 1
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