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ONTOLOGY REPORT - ANNOTATIONS

Term:bilirubin transmembrane transporter activity
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Accession:GO:0015127 term browser browse the term
Definition:Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.
Synonyms:xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region";   Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region";   reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region"
 never_in_taxon: NCBITaxon:4751 ! Fungi

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bilirubin transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:11,593,701...11,686,790
Ensembl chrNW_004624737:11,593,864...11,688,460 		JBrowse link
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  molecular_function 18442
    transporter activity 1152
      transmembrane transporter activity 1051
        organic anion transmembrane transporter activity 246
          carboxylic acid transmembrane transporter activity 163
            dicarboxylic acid transmembrane transporter activity 24
              bilirubin transmembrane transporter activity 1
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