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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium-dependent cysteine-type endopeptidase inhibitor activity
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Accession:GO:0010859 term browser browse the term
Definition:Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.



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calcium-dependent cysteine-type endopeptidase inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin enables IDA
ISO
IEA
IBA
calpain inhibitor
(PMID:2407243)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:2407243 PMID:17429681 GO_REF:0000033 GO_REF:0000107, RGD:1626249 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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  molecular_function 20634
    molecular function regulator activity 2227
      enzyme regulator activity 1360
        enzyme inhibitor activity 440
          peptidase inhibitor activity 208
            endopeptidase inhibitor activity 198
              cysteine-type endopeptidase inhibitor activity 50
                calcium-dependent cysteine-type endopeptidase inhibitor activity 1
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