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alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
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Accession:GO:0008455 term browser browse the term
Definition:Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.
Synonyms:exact_synonym: alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity
 related_synonym: GnTII activity;   N-acetylglucosaminyltransferase II activity;   N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity;   UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity;   UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity;   acetylglucosaminyltransferase II activity;   alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity;   alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity;   uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity;   uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity;   uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity
 xref: EC:2.4.1.143;   MetaCyc:2.4.1.143-RXN;   RHEA:12941;   Reactome:R-HSA-4793955 "Defective MGAT2 does not transfer GlcNAc to N-glycans";   Reactome:R-HSA-9694656 "Spike trimer glycoside chains are extended";   reactome:R-HSA-975829 "Addition of a GlcNAc on the alpha 1,4 branch by MGAT2"

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alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase enables ISO (PMID:12417412)
(PMID:29666272), (PMID:7635144)
(PMID:8808595)		 MGI
UniProt
RGD		 PMID:2952645 PMID:7635144 PMID:8808595 PMID:12417412 PMID:29666272 RGD:1599934 NCBI chrNW_004955409:13,029,578...13,032,406
Ensembl chrNW_004955409:13,030,569...13,031,912 		JBrowse link
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Path 1
Term Annotations click to browse term
  molecular_function 14382
    catalytic activity 3811
      catalytic activity, acting on a protein 1642
        catalytic activity, acting on a glycoprotein 15
          alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 14382
    catalytic activity 3811
      transferase activity 1696
        glycosyltransferase activity 206
          UDP-glycosyltransferase activity 102
            acetylglucosaminyltransferase activity 35
              alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 1
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