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ONTOLOGY REPORT - ANNOTATIONS


Term:cystathionine beta-synthase activity
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Accession:GO:0004122 term browser browse the term
Definition:Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
Synonyms:related_synonym: L-serine hydro-lyase (adding homocysteine);   L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming);   beta-thionase activity;   methylcysteine synthase activity;   serine sulfhydrase activity;   serine sulfhydrylase activity
 xref: EC:4.2.1.22;   MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN;   RHEA:10112;   Reactome:R-HSA-1614524 "PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine"



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cystathionine beta-synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase enables TAS
ISO
IEA
IBA
(PMID:18776696), (PMID:19010420), (PMID:22985361), (PMID:23981774), (PMID:24416422), (PMID:7929220)
GO_REF:0000104
MGI:1857139 (PMID:10953023), (PMID:7878023)
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:7878023 PMID:7929220 PMID:10953023 PMID:18776696 PMID:19010420 More... GO_REF:0000033 GO_REF:0000104, RGD:634704 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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Term Annotations click to browse term
  molecular_function 21086
    catalytic activity 6127
      lyase activity 214
        carbon-oxygen lyase activity 89
          hydro-lyase activity 69
            cystathionine beta-synthase activity 1
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