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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA polymerase II activity
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Accession:GO:0001055 term browser browse the term
Definition:Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
Synonyms:exact_synonym: DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter
 xref: reactome:R-HSA-6814549 "Pre-snRNA transcript initiation, Integrator binding, LEC binding";   reactome:R-HSA-6814559 "Pre-snRNA is elongated and capped with 7-methylguanosine"

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RNA polymerase II activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polr2a RNA polymerase II subunit A enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624786:10,098,133...10,122,783
Ensembl chrNW_004624786:10,097,294...10,122,893 		JBrowse link
G Polr2b RNA polymerase II subunit B enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:12,387,553...12,430,211
Ensembl chrNW_004624761:12,387,553...12,430,871 		JBrowse link
G Polr2c RNA polymerase II subunit C enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624746:28,604,098...28,612,975
Ensembl chrNW_004624746:28,604,098...28,613,006 		JBrowse link
G Polr2e RNA polymerase II, I and III subunit E enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624828:7,547,401...7,553,282
Ensembl chrNW_004624828:7,547,460...7,553,282 		JBrowse link
G Polr2f RNA polymerase II, I and III subunit F enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:9,978,373...9,988,192
Ensembl chrNW_004624752:9,978,273...9,988,134 		JBrowse link
G Polr2h RNA polymerase II, I and III subunit H enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:72,221,964...72,228,133
Ensembl chrNW_004624730:72,221,964...72,228,616 		JBrowse link
G Polr2j RNA polymerase II subunit J enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624740:15,169,414...15,174,212
Ensembl chrNW_004624740:15,169,459...15,173,805 		JBrowse link
G Polr2k RNA polymerase II, I and III subunit K enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624763:7,068,000...7,071,752
Ensembl chrNW_004624763:7,068,012...7,071,799 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 16258
    catalytic activity 5070
      catalytic activity, acting on a nucleic acid 565
        catalytic activity, acting on RNA 347
          RNA polymerase activity 23
            5'-3' RNA polymerase activity 23
              DNA-directed 5'-3' RNA polymerase activity 22
                RNA polymerase II activity 8
Path 2
Term Annotations click to browse term
  molecular_function 16258
    catalytic activity 5070
      transferase activity 2174
        transferase activity, transferring phosphorus-containing groups 913
          nucleotidyltransferase activity 110
            RNA polymerase activity 23
              5'-3' RNA polymerase activity 23
                DNA-directed 5'-3' RNA polymerase activity 22
                  RNA polymerase II activity 8
paths to the root